Chinwe Ekenna

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Probabilistic Roadmap Methods (PRMs) are widely used motion planning methods that sample robot configurations (nodes) and connect them to form a graph (roadmap) containing feasible trajectories. Many PRM variants propose different strategies for each of the steps and choosing among them is problem dependent. Planning in heterogeneous environments and/or on(More)
Modeling large-scale protein motions, such as those involved in folding and binding interactions, is crucial to better understanding not only how proteins move and interact with other molecules but also how proteins misfold, thus causing many devastating diseases. Robotic motion planning algorithms, such as Rapidly Exploring Random Trees (RRTs), have been(More)
Probabilistic Roadmap Methods (PRMs) solve the motion planing problem by constructing a roadmap (or graph) that models the motion space when feasible local motions exist. PRMs and variants contain several phases during roadmap generation i.e., sampling, connection, and query. Some work has been done to apply machine learning to the connection phase to(More)
Protein folding plays an essential role in protein function and stability. Despite the explosion in our knowledge of structural and functional data, our understanding of protein folding is still very limited. In addition, methods such as folding core identification are gaining importance with the increased desire to engineer proteins with particular(More)
Simulating protein folding motions is an important problem in computational biology. Motion planning algorithms, such as Probabilistic Roadmap Methods, have been successful in modeling the folding landscape. Probabilistic Roadmap Methods and variants contain several phases (i.e., sampling, connection, and path extraction). Most of the time is spent in the(More)
In this paper we present a simulated annealingbased method for planning efficient paths with a tether which avoid entanglement in an obstacle-filled environment. By evaluating total path cost as a function of both path length and entanglements, a robot can plan a path through multiple points of interest while avoiding becoming entangled in any obstacle. In(More)
Sampling-Based Motion Planning (SBMP) has been successful in planning the motion for a wide variety of robot types. An important primitive of these methods is selecting candidate neighbors and validating/invalidating the pathways between nodes of the map. These neighbors are commonly selected based on some distance metric (DM). An ideal distance metric for(More)
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