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cDNA Cloning and Immunological Characterization of a Newly Identified Enolase Allergen from Penicillium citrinum and Aspergillus fumigatus
Background:Penicillium citrinum and Aspergillus fumigatus are prevalent indoor airborne fungal species that have been implicated in human respiratory allergic disorders. It is important to understandExpand
Keloid-derived fibroblasts have a diminished capacity to produce prostaglandin E2.
Keloids result from pathological wound healing responses. However, the pathogenesis of keloids is still poorly understood. PGE2 was shown to decrease fibroblast proliferation, inhibit collagenExpand
Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter
Purpose Myeloid differentiation-2 (MD-2) has been associated with endotoxin and inflammatory disorders because it can recognize lipopolysaccharide (LPS) binding and attenuate Toll-like receptor 4Expand
The prevalence of IgE antibody reactivity against the alkaline serine protease major allergen of Penicillium chrysogenum increases with the age of asthmatic patients.
BACKGROUND Penicillium species are prevalent airborne fungi. However, the prevalence of allergic sensitization to Penicillium antigens and the true impact of these ubiquitous fungi on atopicExpand
Statin-conferred enhanced cellular resistance against bacterial pore-forming toxins in airway epithelial cells.
Statins are widely used to prevent cardiovascular disease. In addition to their inhibitory effects on cholesterol synthesis, statins have beneficial effects in patients with sepsis and pneumonia,Expand
Der p2 Internalization by Epithelium Synergistically Augments Toll-like Receptor-Mediated Proinflammatory Signaling
Purpose House-dust-mite (HDM) major allergen Der p2 shares homology and function with Toll-like receptor (TLR) signaling protein myeloid differentiation-2 (MD2) and may lead to airway inflammation.Expand
Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19
Background Physicians treating COVID-19 patients increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a cytokine storm. TheExpand
A Vacuolar Serine Protease (Rho m 2) Is a Major Allergen of Rhodotorula mucilaginosa and Belongs to a Class of Highly Conserved Pan-Fungal Allergens
Background:Rhodotorula mucilaginosa is one of the most frequently encountered species of yeasts in our environment. We reported here a major allergen of R. mucilaginosa. Methods: A major R.Expand
Characterization of Enolase Allergen from Rhodotorula mucilaginosa
Rhodotorula mucilaginosa (also known as R. rubra) is among the most commonly found yeast strains in our environment. However, allergens from R. mucilaginosa have not yet been characterized at theExpand
Characterization of enolase allergen from Rhodotorula mucilaginosa.
Rhodotorula mucilaginosa (also known as R. rubra) is among the most commonly found yeast strains in our environment. However, allergens from R. mucilaginosa have not yet been characterized at theExpand
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