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Reading in a second language (L2) is a complex task that entails an interaction between L2 and the native language (L1). To study the underlying mechanisms, we used functional magnetic resonance imaging (fMRI) to visualize Chinese-English bilinguals' brain activity in phonological processing of logographic Chinese and alphabetic English, two written(More)
The accurate detection of deception or lying is a challenge to experts in many scientific disciplines. To investigate if specific cerebral activation characterized feigned memory impairment, six healthy male volunteers underwent functional magnetic resonance imaging with a block-design paradigm while they performed forced-choice memory tasks involving both(More)
The changes in regional cerebral blood flow (rCBF) associated with the changes in neuronal activity are routinely measured both by positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) techniques. However, direct comparison has not been performed to determine similarities and differences of PET and fMRI techniques in(More)
Converging lines of research in neuroimaging recognize selection as one of the critical functions of prefrontal cortex (e.g., see Annu. Rev. Neurosci. 24, 2001 167). We examined a central thesis of a selection hypothesis (Neuropsychologia 41, 2003 280) that the left inferior frontal gyrus (LIFG) serves as a general mechanism for selecting among competing(More)
Dynamic changes in the cerebral metabolic rate of oxygen (CMRO(2)) and oxygen extraction ratio (OER) in an event-related functional MRI (ER-fMRI) were measured in this study. Six subjects participated in this study at a magnetic field of 1.9 T. Cerebral blood flow (CBF) and blood oxygenation level-dependent (BOLD) changes were acquired during the brief(More)
PURPOSE To compare the temporal behaviors of perfusion and blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) in the detection of timing differences between distinct brain areas, and determine potential latency differences between stimulus onset and measurable fMRI signal in sensory cortices. MATERIALS AND METHODS(More)
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