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Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behavior
Optogenetics and new optical tools are used to manipulate neural activity directly in freely moving animals to evoke chemotactic behaviour and it is discovered that controlling the dynamics of activity in just one interneuron pair (AIY) was sufficient to force the animal to locate, turn towards and track virtual light gradients.
A Compressed Sensing Framework for Efficient Dissection of Neural Circuits
This work describes a compressed sensing-based framework in combination with non-specific genetic tools to infer candidate neurons controlling behaviors with fewer measurements than previously thought possible and suggests that compressed sensing approaches can be used to identify key nodes in complex biological networks.
Dynamics of Neural Activity During Chemotaxis in Caenorhabditis Elegans
It is discovered that controlling the activity in just one pair of interneurons (AIY) is sufficient to manipulate the animal to locate, turn towards and track a virtual light gradient.