Chin-Chye Lim

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The aim of the present study was to investigate how night duties can affect the circadian rhythms of military personnel working onboard a naval ship. Twenty individuals on a regular day-work schedule from 9:00 a.m. to 6:00 p.m. (serving as controls) and 40 individuals on night-shift duties participated in the study. Salivary melatonin and cortisol profiles(More)
This study examined the effects of one night of sleep deprivation on melatonin and cortisol profiles, as well as performance efficiency of military service members. Sleep intervention consisted of total lack of sleep (N = 7) or 8 hours of sleep (control group; N = 7) during the night. All parameters were measured at selected time intervals before (day 1),(More)
As data on procalcitonin utility in antibiotics discontinuation [under an antimicrobial stewardship program (ASP)] in patients with malignancies are lacking, we aimed to evaluate the utility of procalcitonin in an ASP in patients with malignancies. We conducted a retrospective review of the ASP database of all patients with malignancies in whom at least one(More)
The medical attrition rates of 4 cohorts of recruits undergoing basic military training (BMT) were studied. They were grouped as follows: Group A (n = 3475), a mixture of fit and unfit recruits; Group B (n = 2081), consisting only of fit recruits; Group C (n = 940) comprising only unfit recruits who underwent a 4 to 6 weeks conditioning programme prior to(More)
This study investigates the effects of long-term passive heat exposure and a 16-week basic military training program on heat acclimatization. Thirty recruits were tested on the zero (T1), 2nd (T2), 6th (T3), and 16th (T4) weeks of the basic military training program. The trials involved 1 hour of marching on a treadmill at 5.5 km h-1, with a 5% gradient.(More)
The purpose of this study was to compare 2.4-km running performance in 2,639 smoking (SM) and nonsmoking (NS) male conscripts aged 18 to 26 years. Maximum oxygen consumption (VO2max) and aerobic exercise endurance were also compared between SM and NS subjects (N = 156) stratified into various running performance bands. SM subjects ran significantly slower(More)
We attempted to determine whether persons susceptible to heatstroke produced higher serum concentrations of interleukin-6, tumor necrosis factor-alpha, and interleukin-10 when subjected to heat stress. Nine patients with previous heatstroke and 21 matched controls were subjected to a heat-stress test (at 32 degrees C, 67% humidity, 900 W/m2 solar radiation,(More)
Forty of the most obese recruits going through a 20 weeks Basic Military Training (BMT) program were selected from a cohort of 197 obese recruits. Their TBW, BF, FFW, VO2max, time taken to achieve VT (VTTime) and maximal heart rate (HRmax) were measured before, in the middle, and at the end of the program. The means for each of these variables measured in(More)
The Singapore Armed Forces (SAF) Medical Corps and the Ministry of Health (MOH) have published clinical practice guidelines on Management of Heat Injury to provide doctors and patients in Singapore with evidence-based guidance on the prevention and clinical management of exertional heat injuries. This article reproduces the introduction and executive(More)
BACKGROUND DNA repair pathways play a crucial role in maintaining the human genome. Previous studies associated DNA repair gene polymorphisms (XPD Lys751Gln, XRCC1 Arg280His and XRCC1 Arg399Gln) with nasopharyngeal carcinoma. These non-synonymous polymorphisms may alter DNA repair capacity and thus increase or decrease susceptibility. The present study(More)