Chikahiro Takita

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STUDY DESIGN A retrospective clinical study. OBJECTIVES To show the prevalence of deep venous thrombosis (DVT) and pulmonary embolism (PE) after spinal surgery using a D-dimer assay followed by screening with computed tomographic (CT) pulmonary angiography and CT venography. SUMMARY OF BACKGROUND DATA A few studies on DVT development after spinal(More)
Peripheral blood mononuclear cells (PBMCs) obtained from atopic dermatitis (AD) patients produced low levels of IFN-gamma in response to Dermatophagoides farinae antigen (Der f Ag) plus IL-2 or OKT3 MoAb in contrast with PBMCs obtained from healthy donors. The reduced IFN-gamma production in AD patients' T cells appeared to be derived from the defect of(More)
In the present study, we aimed to determine whether tacrolimus (FK506) and cyclosporine A act directly on human osteoclast precursors obtained from patients with rheumatoid arthritis (RA) and influence monocyte–osteoclast differentiation induced by receptor activator of NF-κB ligand (RANKL) in vitro, the stage at which differentiation was affected and the(More)
Infliximab is known to protect against the development of joint destruction. In the present study, we sought to determine whether Infliximab acts directly on human osteoclast precursors and influences monocyte-osteoclast differentiation induced by receptor activator of nuclear factor kappaB ligand (RANKL) in vitro. Peripheral blood mononuclear cells (PBMCs)(More)
STUDY DESIGN Retrospective cross-sectional study. OBJECTIVE This study aimed to elucidate the relationship between developmental spinal canal stenosis (DCS) and morphologic features in the cervical spine by comparing the features between DCS and nondevelopmental spinal canal stenosis (NDCS). SUMMARY OF BACKGROUND DATA DCS is an important predisposing(More)
The inducible prostaglandin synthesis enzyme, cyclooxygenase-2 (COX-2), is involved in bone resorption and osteoclastogenesis, and acts indirectly through prostaglandin E2 (PG E2) produced by osteoblastic cells. This study was undertaken to investigate whether celecoxib (a selective COX-2 inhibitor) has a direct effect on human osteoclast precursors to(More)
STUDY DESIGN Retrospective cross-sectional study. OBJECTIVE This study aimed to elucidate the relationship among facet orientation, kinematics of a spinal unit, and change in lumbar spine canal diameter by using kinetic magnetic resonance imaging. SUMMARY OF BACKGROUND DATA Some studies have suggested an association between increased sagittally oriented(More)
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