Chih-Hao Lai

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BACKGROUND Both alcoholism and heroin dependence are common substance use disorders with a high genetic basis. A recent genetic study reported that the autism susceptibility candidate 2 gene (AUTS2) was involved in regulating the alcohol drinking behavior. In our previous total gene expression profiling study, we found that the AUTS2 transcript was(More)
Heroin dependence is a complex mental disorder resulting from interactions between genetic and environmental factors. Identifying the susceptibility genes of heroin dependence is the basis for understanding the pathogenesis of heroin dependence. Using a total gene expression microarray, we detected 924 differentially expressed gene transcripts in(More)
OBJECTIVE Copy number variations encompassing the chromosome 15q11-q13 region have been implicated in the pathogenesis of several neurodevelopmental disorders including schizophrenia. The study aimed to investigate whether the GABRB3 gene mapped to 15q12 was associated with schizophrenia. MATERIALS AND METHODS We resequenced the promoter and all the(More)
In Orthogonal Frequency Division Multiplex based system, inter-cell interference is an important issue which impacts signal quality between base stations and user equipments (UEs), especially for UEs at cell edge. In order to relieve this problem, Third Generation Partnership Project Long Term Evolution defines high interference indicator (HII) and overload(More)
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