Chih-Chan Lin

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BACKGROUND Although various alterative models of therapy are used for cartilage repair, no definite conclusion has been reached. Glucosamine (GlcN) is widely used as a nutritional supplement. However, the clinical- evidence-based outcome of GlcN administration remains controversial. N-acetyl-D-glucosamine (GlcNAc), a derivative of GlcN, shows(More)
Downward remodelling of gap junctional proteins between myocytes may trigger ventricular arrhythmia after myocardial infarction. We have demonstrated that ATP-sensitive potassium (K(ATP)) channel agonists attenuated post-infarction arrhythmias. However, the involved mechanisms remain unclear. The purpose of this study was to determine whether K(ATP) channel(More)
In this article, we propose a symbolic simulation method where Boolean functions can be efficiently manipulated through a 2-domain partitioned OBDD data structure. The functional partition is applied by automatically exploring the key decision points implicitly built inside a circuit. The partition can help to significantly reduce the OBDD sizes, solving(More)
In this paper, we provide a flexible and automatic method to partition the functional space for efficient symbolic simulation. We utilize a 2-tuple list representation as the basis for partitioning the functional space. The partitioning is carried out dynamically during the symbolic simulation based on the sizes of OBDDs. We develop heuristics for choosing(More)
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