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The potential pharmacologic mechanisms of omalizumab in patients with chronic spontaneous urticaria.
In patients given a diagnosis of chronic spontaneous urticaria (CSU), there are no obvious external triggers, and the factors that initiate the clinical symptoms of wheal, flare, and itch arise fromExpand
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Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations.
IgE mediates hypersensitivity reactions responsible for most allergic diseases, which affect 20-40% of the population in developed countries. A 52-residue domain of membrane-bound IgE (mIgE) calledExpand
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Basal Cell Nevus Syndrome in a Family
Basal cell nevus syndrome is also named Nevoid basal cell carcinoma syndrome (NBCCS) or Gorlin syndrome. Multiple organ systems may be involved, including skin, skeletal system, genitourinary systemExpand
Langerhans Cell Histiocytosis with Lungs and One Rib Involvement: a case report
Pulmonary Langerhans cell histiocytosis (LCH) is a rare disease. The typical findings on chest computed tomography (CT) of this disease are multiple bizarre cystic spaces associated with smallExpand