Chieko Ishiguro

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BACKGROUND Antihypertensive and non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat many common diseases. However, it has been suspected that interactions between these drugs exist. Here, we assessed the interactions between non-selective NSAIDs and several classes of antihypertensive drugs. METHODS The study design was a cohort study using(More)
BACKGROUND Delirium is a common and serious clinical problem for hospitalized patients and is associated with an increased risk of morbidity and mortality and increased healthcare costs. OBJECTIVE The objective of this study was to investigate the preliminary usefulness of a novel delirium training program to improve nurses' self-confidence in caring for(More)
Drug Safety Communications (DSCs), a major tool for risk communication used by the US Food and Drug Administration (FDA), are also designed to encourage spontaneous reporting. However, the effectiveness of this tool remains unclear. The objectives of this study were to evaluate changes in the frequency of spontaneous reporting before and after the release(More)
Drug agencies and pharmaceutical companies are responsible for continuously monitoring drug safety profiles to implement necessary safety measures. Retrospective analyses of safety-related regulatory actions (SRRAs) are known to be helpful as a tool for evaluating postmarketing safety in Western countries. However, few studies have examined the relationship(More)
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