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A study in healthy male volunteers was completed to evaluate the safety, tolerability, and pharmacokinetics of a single oral dose of the antiparasitic moxidectin (MOX). This drug is registered worldwide as a veterinary antiparasitic agent for use in companion and farm animals. This is the first study of MOX in humans. All subjects were between the ages of(More)
We are what we eat. Our everyday food choices affect our long-term and short-term health. In the traditional health care, professionals assess and weigh each individual's dietary intake using intensive labor at high cost. In this paper, we design and implement a diet-aware dining table that can track what and how much we eat. To enable automated food(More)
A visibility representation of a graph G is to represent the nodes of G with non-overlapping horizontal line segments such that the line segments representing any two distinct adjacent nodes are vertically visible to each other. If G is a plane graph, i.e., a planar graph equipped with a planar embedding, a visibility representation of G has the additional(More)
PARP1 and poly(ADP-ribosyl)ation (PARylation) have been shown to be essential for the initial steps of cellular reprogramming. However, the mechanism underlying PARP1/PARylation-regulated activation of pluripotency loci remains undetermined. Here, we demonstrate that CHD1L, a DNA helicase, possesses chromatin remodeling activity and interacts with(More)
The Ages & Stages Questionnaire: Social-Emotional (ASQ:SE; Squires, Bricker, & Twombly, 2002a), developed in the United States, was translated and adapted for use in China. Lack of valid and reliable instruments for identifying social and emotional delays in young children is a worldwide issue. Professionals in China have recently focused efforts on(More)
Acknowledgments This research started in April 2005 and is a joint work among several students and faculty members. First of all, I would like to dedicate many thanks to my advisor Prof. Hao-hua Chu for his energy and advice contributed to this project. I have learned a lot from him under the collaboration in this project, from research investigation, group(More)
To examine how frequently and confidently healthy women report symptoms during surveillance for ovarian cancer. A symptoms questionnaire was administered to 24,526 women over multiple visits accounting for 70,734 reports. A query of reported confidence was included as a confidence score (CS). Chi square, McNemars test, ANOVA and multivariate analyses were(More)
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