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  • Chiara Luberto, Daniel Hassler, +7 authors G. Kenneth Smith
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2002 (First Publication: 25 October 2002)
  • A high throughput screen for neutral, magnesium-dependent sphingomyelinase (SMase) was performed. One inhibitor discovered in the screen, GW4869, functioned as a noncompetitive inhibitor of theExpand
  • Hélène Birbes, Chiara Luberto, Yi-Te Hsu, Samer El Bawab, Yusuf A. Hannun, Lina M. Obeid
  • Medicine, Biology
  • The Biochemical journal
  • 2005 (First Publication: 15 March 2005)
  • We recently showed that targeting bSMase (bacterial sphingomyelinase) specifically to mitochondria caused accumulation of ceramide in mitochondria, and induced cytochrome c release and cell deathExpand