Chiara Brachelente

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BACKGROUND Flea allergy dermatitis (FAD) is a common skin disease in dogs and can be induced experimentally. It often coexists with other allergic conditions. So far no studies have investigated the quantitative production of cytokine mRNA in skin biopsies and peripheral blood mononuclear cells (PBMC) in flea allergic dogs. OBJECTIVE The aim of our study(More)
M. Sforna, C. Brachelente, E. Lepri and L. Mechelli Department of Veterinary Biopathological Sciences, Section of Veterinary Pathology and Hygiene, Faculty of Veterinary Medicine, University of Perugia, 06126 Perugia, Italy *Correspondence: Dipartimento di Scienze Biopatologiche Veterinarie, Sezione di Patologia ed Igiene Veterinaria, Facoltà di Medicina(More)
Skin lesions are a frequent manifestation of Leishmania infantum infections in Mediterranean countries. This study demonstrates by real-time reverse transcriptase-polymerase chain reaction the local cytokine response in skin biopsies from Leishmania-infected dogs (n=10). As controls, we investigated skin biopsies from healthy (n=10) and fleabite(More)
BACKGROUND Exfoliative dermatitis has been described in cats as a paraneoplastic skin disease associated with thymoma. There are anecdotal reports of cases without thymoma, with various suspected aetiologies. HYPOTHESIS/OBJECTIVES To identify common features, underlying causes, response to therapy and outcome of nonthymoma-associated exfoliative(More)
BACKGROUND Epithelial-to-mesenchymal transition (EMT) is a multistep process, important in tumour invasion and metastasis, characterized by loss of epithelial markers, redistribution of β-catenin and gain of mesenchymal markers. HYPOSTHESIS/OBJECTIVES: Our aim was to investigate the immunohistochemical aberrant expression of cytokeratin, vimentin, survivin(More)
The aim of this study was to evaluate the presence of Helicobacter (H.) spp. in swine affected by gastric ulceration. Stomachs from 400 regularly slaughtered swine were subjected to gross pathological examination to evaluate the presence of gastric ulcers. Sixty-five samples collected from ulcerated pars esophagea and 15 samples from non-ulcerated pyloric(More)
BACKGROUND Although cutaneous stem cells have been implicated in skin tumourigenesis in humans, no studies have been conducted to elucidate the presence and the possible role of stem cells in hair follicle tumours in the dog. HYPOTHESIS Stem cell markers are expressed in canine epidermal and follicular tumours and can be used to better understand the(More)
A. Spaterna1*, L. Mechelli2, F. Rueca3, M. Cerquetella1, C. Brachelente2, M.T. Antognoni3 and B. Tesei1 1Veterinary Science Department, Clinical Section, Faculty of Veterinary Medicine, University of Camerino, 62024 Matelica, Macerata, Marche; 2Veterinary Biopathological Science Department; 3Veterinary Pathology, Diagnostic and Clinic Department, Section of(More)
Congenital hepatic fibrosis is a disorder of biliary system development histologically characterized by diffuse periportal to bridging fibrosis with numerous small often-irregular bile ducts and reduction in the number of portal vein branches. The condition results from abnormal development of the ductal plate, the embryonic precursor to the interlobular(More)