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  • Po-Min Shih, Iren Wang, +7 authors Shang-Te Danny Hsu
  • Chemistry, Medicine
  • The journal of physical chemistry. B
  • 2015 (First Published: 30 April 2015)
  • Recent studies on the mechanisms by which topologically knotted proteins attain their natively knotted structures have intrigued theoretical and experimental biophysicists. Of particular interest isContinue Reading
  • Chia-Yun Chang, Ming-Tsung Hsu, Emilio Xavier Esposito, Yufeng Jane Tseng
  • Chemistry, Medicine, Computer Science
  • Journal of Chemical Information and Modeling
  • 2013 (First Published: 22 April 2013)
  • The traditional biological assay is very time-consuming, and thus the ability to quickly screen large numbers of compounds against a specific biological target is appealing. To speed up theContinue Reading
  • Yun-Tzai Cloud Lee, Chia-Yun Chang, Szu-Yu Chen, Yun-Ru Pan, Meng-Ru Ho, Shang-Te Danny Hsu
  • Chemistry, Medicine
  • Scientific reports
  • 2017 (First Published: 1 May 2017)
  • Human ubiquitin C-terminal hydrolyase UCH-L5 is a topologically knotted deubiquitinase that is activated upon binding to the proteasome subunit Rpn13. The length of its intrinsically disorderedContinue Reading