Chia-Wen Liu

Hwei-Fang Tien2
Jih-Luh Tang2
Shang-Yi Huang2
2Hwei-Fang Tien
2Jih-Luh Tang
2Shang-Yi Huang
2Ying-Chieh Chiang
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Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing in 500 patients with de novo AML and analysed their(More)
BACKGROUND Robo4 is involved in hematopoietic stem/progenitor cell homeostasis and essential for tumor angiogenesis. Expression of Robo4 was recently found in solid tumors and leukemia stem cells. However, the clinical implications of Robo4 expression in patients with acute myeloid leukemia (AML) remain unclear. METHODS We investigated the clinical and(More)
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