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A Genome-Wide Association Study Reveals a Quantitative Trait Locus of Adiponectin on CDH13 That Predicts Cardiometabolic Outcomes
OBJECTIVE The plasma adiponectin level, a potential upstream and internal facet of metabolic and cardiovascular diseases, has a reasonably high heritability. Whether other novel genes influence theExpand
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Diabetes Mellitus and the Risk of Alzheimer’s Disease: A Nationwide Population-Based Study
Objectives Possible association between diabetes mellitus (DM) and Alzheimer’s disease (AD) has been controversial. This study used a nationwide population-based dataset to investigate theExpand
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Purpose: To investigate the incidence and risk factors for central serous chorioretinopathy (CSCR) in adults who use oral corticosteroids in Taiwan. Methods: This is a population-based nestedExpand
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Epidemiology of Idiopathic Central Serous Chorioretinopathy in Taiwan, 2001–2006: A Population-based Study
Objectives The epidemiology of idiopathic central serous chorioretinopathy (CSCR) is not well understood in an Asian population. The present study aimed to investigate the incidence and risk factorsExpand
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Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as Hypertension Susceptibility Genes in Han Chinese with a Genome-Wide Gene-Based Association Study
Hypertension is a complex disorder with high prevalence rates all over the world. We conducted the first genome-wide gene-based association scan for hypertension in a Han Chinese population. ByExpand
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Gastroesophageal Reflux Disease and Atrial Fibrillation: A Nationwide Population-Based Study
Objectives Precise mechanisms of atrial fibrillation (AF) are uncertain, but their association with esophageal disorders has been recently proposed. The association between gastroesophageal refluxExpand
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Genome-Wide Association Study of Young-Onset Hypertension in the Han Chinese Population of Taiwan
Young-onset hypertension has a stronger genetic component than late-onset counterpart; thus, the identification of genes related to its susceptibility is a critical issue for the prevention andExpand
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Oral alendronate use and risk of cancer in postmenopausal women with osteoporosis: A nationwide study
The association between use of oral bisphosphonates and cancer development in elderly women is still uncertain, and previous studies have shown controversial results. We used a nationwide,Expand
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Genetic variants of connexin37 are associated with carotid intima-medial thickness and future onset of ischemic stroke.
BACKGROUND Carotid intima-medial thickness (IMT) is a surrogate marker of subclinical atherosclerosis. This study aimed to investigate the impacts of genetic variants on IMT and future development ofExpand
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Angiotensin-receptor blockers and risk of Alzheimer's disease in hypertension population--a nationwide cohort study.
BACKGROUND Although emerging evidence shows angiotensin-receptor blockers (ARBs) may have a beneficial effect against Alzheimer's disease (AD), the association is not consistent. We investigated theExpand
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