Chia-Jen Chang

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We employed second-harmonic generation (SHG) imaging and the zebrafish model to investigate the myopathy caused by statin in vivo with emphasis on the altered microstructures of the muscle sarcomere, the fundamental contractile element of muscles. This approach derives an advantage of SHG imaging to observe the striated skeletal muscle of living zebrafish(More)
PURPOSE Past studies present evidence of associations between air pollution and human ocular symptoms; however, to the knowledge of the authors, research investigating the hazardous effects of air pollution on nonspecific conjunctivitis is nonexistent. This study investigates the relationship between air pollution and outpatient visits for nonspecific(More)
In this paper, we design and implement a testbed to realize various experiments in heterogeneous wireless sensor networks. Our implementation includes hardware infrastructure and software framework. The hardware infrastructure consists of servers, gateways with converters, and sensor nodes in three-tier. Our testbed can support different sensor nodes with(More)
Learned resourcefulness may be an important and necessary resource for people with diabetes to adequately manage their disease. This study used a cross-sectional, descriptive correlation design to examine the relationships of demographic characteristics, stressors, learned resourcefulness, and depressive symptoms among adult Taiwanese with diabetes(More)
The 3D IC is an emerging technology. The primary emphasis on 3D-IC routing is the interface issues across dies. To handle the interface issue of connections, the inter-die routing, which uses micro bumps and two single-layer RDLs (Re-Distribution Layers) to achieve the connection between adjacent dies, is adopted. In this paper, we present an inter-die(More)
Tridiagonal solvers are important building blocks for a wide range of scientific applications that are commonly performance-sensitive. Recently, many-core architectures, such as GPUs, have become ubiquitous targets for these applications. Therefore, a high-performance general-purpose GPU tridiagonal solver becomes critical. However, no existing GPU(More)
Carcinoma ex pleomorphic adenoma affects glandular structures, occurring mostly in major salivary glands and less commonly in the lacrimal gland. We present a rare case in the lacrimal gland. We highlight the importance of keeping this rare tumor in mind and the early detection of symptoms because such a malignant transformation could occur in pleomorphic(More)
PURPOSE In normal tension glaucoma (NTG), factors other than elevated intraocular pressure are likely to have a role in the pathogenesis of optic neuropathy. Recent studies of glaucoma or retinal ganglion cells (RGCs) reveal that the cytokine interleukin-6 (IL-6) is linked to the pathogenesis of glaucoma and may regulate RGC survival or death. The IL-6(More)
PURPOSE Underestimation of IOP in a myopic patient may lead to misjudgment of the risk of glaucoma. This study investigated the influence of orthokeratology-induced change in CCT on IOP measured by the non-contact pneumotonometer (NCT), Goldmann applanation tonometer (GAT), and Pascal dynamic contour tonometer (PDCT). METHODS This study was conducted to(More)