Chia-Ching Lee

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If fear memory is expressed by a long-term potentiation (LTP) of synaptic transmission in the amygdala, then reversal of LTP (depotentiation) in this area of the brain may provide an important mechanism for amelioration of anxiety and post-traumatic stress disorder. Herein, we show that low-frequency stimulation (LFS) of the external capsule elicits a(More)
There is a close correlation between long-term potentiation (LTP) in the synapses of lateral amygdala (LA) and fear conditioning in animals. We predict that reversal of LTP (depotentiation) in this area of the brain may ameliorate conditioned fear. Activation of group II metabotropic glutamate receptors (mGluR II) with DCG-IV induces depotentiation in the(More)
The holding power of the bone-screw interfaces is one of the key factors in the clinical performance of screw design. The value of the holding power can be experimentally measured by pullout tests. Historically, some researchers have used the finite-element method to simulate the holding power of the different screws. Among them, however, the assumed(More)
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