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- Yau-Hung Chen, Yi-Hui Christine Huang, +4 authors H T Tsay
- Neurotoxicology and teratology
- 2008
Though caffeine is broadly distributed in many plants and foods, little is known about the teratogenic effects of caffeine during early embryonic development. Here, we used zebrafish as a model to… (More)
- Chien-Hung Yeh, Yun-feng Liao, +5 authors Yau-Hung Chen
- Drug and chemical toxicology
- 2012
Caffeine is a widely consumed substance that occurs in numerous dietary sources, but teratogenic effects of caffeine intake during embryonic development are still not clear. In the present study, we… (More)
Shape restricted regressions, including isotonic regression and concave regression as special cases, are studied using priors on Bernstein polynomials and Markov chain Monte Carlo methods. These… (More)
- Yau-Hung Chen, Zhi-Shiang Yang, +4 authors T. Shih
- Food chemistry
- 2012
The antioxidant ability of an array of commercially available flavonoids was evaluated on the larvae of the zebrafish model organism, in order to find flavonoids with lower toxicities and higher… (More)
- Yau-Hung Chen, Chi-Chung Wen, Chun-Yun Lin, Chi-Yuan Chou, Zhi-Shiang Yang, Yun-Hsin Wang
- Toxicology mechanisms and methods
- 2011
This study applied broccoli and cauliflower extracts (whole, floret, and stem) to zebrafish larvae in parallel to receive 100 mJ/cm(2) of UVB six times, and recorded their fin malformation… (More)
- Chi-Chung Wen, Chien-Tai Lin
- Biometrics
- 2011
Statistical inference based on right-censored data for the proportional hazards (PH) model with missing covariates has received considerable attention, but interval-censored or current status data… (More)
A profile likelihood inference is made for the regression coefficient and frailty parameters in the correlated gamma-frailty model for current status family data. With the introduction of an… (More)
- Michael Olivier, Chao A. Hsiung, +10 authors David R. Cox
- Human molecular genetics
- 2004
Protein tyrosine phosphatase 1beta (PTP-1beta) is involved in the regulation of several important physiological pathways. It regulates both insulin and leptin signaling, and interacts with the… (More)
- Hsi-Chu Peng, Yun-Hsin Wang, Chi-Chung Wen, Wei Wang, C W Cheng, Yau-Hung Chen
- Comparative biochemistry and physiology…
- 2010
We used a green fluorescent kidney line, Tg(wt1b:GFP), as a model to access the acetaminophen (AAP)-induced nephrotoxicity dynamically. Zebrafish (Danio rerio) embryos at different developmental… (More)
- Yau-Hung Chen, Wei Wang, Yun-Hsin Wang, Zi-Yu Lin, Chi-Chung Wen, Ching-Yuh Chern
- Molecules
- 2013
The aim of this study was to investigate novel chalcones with potent anti-inflammatory activities in vivo. Chalcone and two chalcone analogues (compound 5 and 9) were evaluated using a caudal… (More)