Chi-Chung Chan

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BACKGROUND Essential thrombocythemia (ET) is a clonal myeloproliferative disease associated with thrombohemorrhagic complications and myeloid transformation to diseases such as myelofibrosis and acute myeloid leukemia. METHODS A multicenter study was conducted among 231 consecutive Chinese patients with ET. The literature about leukemogenic risk(More)
Lack of clinically relevant tumor models dramatically hampers development of effective therapies for hepatocellular carcinoma (HCC). Establishment of patient-derived xenograft (PDX) models that faithfully recapitulate the genetic and phenotypic features of HCC becomes important. In this study, we first established a cohort of 65 stable PDX models of HCC(More)
Hepatocellular carcinoma (HCC) is the fifth most common type of cancers worldwide. However, current therapeutic approaches for this epidemic disease are limited, and its 5-year survival rate hasn't been improved in the past decades. Patient-derived xenograft (PDX) tumor models have become an excellent in vivo system for understanding of disease biology and(More)
Radio Frequency Identification (RFID) middleware is often regarded as the central nervous system of RFID systems. In this paper, a lightweight RFID middleware is designed and implemented without the need of an Application Level Events (ALE) structure, and its implementation process is described using a typical commerical enterprise. A short review of the(More)
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