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Effective inhibition of MERS-CoV infection by resveratrol
BackgroundMiddle East Respiratory Syndrome coronavirus (MERS-CoV) is an emerging viral pathogen that causes severe morbidity and mortality. Up to date, there is no approved or licensed vaccine orExpand
Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy
IntroductionThe objective of this study was to investigate the effects of tumor necrosis factor (TNF)-α inhibitors on circulating T helper-type 17 (Th17) cells and Th17-related cytokines in patientsExpand
Effect of resveratrol and pterostilbene on aging and longevity
Over the past years, several studies have found that foods rich in polyphenols protect against age‐related disease, such as atherosclerosis, cardiovascular disease, cancer, arthritis, cataracts,Expand
Nortriptyline induces mitochondria and death receptor-mediated apoptosis in bladder cancer cells and inhibits bladder tumor growth in vivo.
Nortriptyline (NTP), an antidepressant, has antitumor effects on some human cancer cells, but its effect on human bladder cancer cells is not known. In this study, we used a cell viability assay toExpand
Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease
IntroductionThe objective of this study was to investigate the potential role of the Toll-like receptor 7 (TLR7) signaling pathway in the pathogenesis of adult-onset Still's diseaseExpand
Significant effects of biologic therapy on lipid profiles and insulin resistance in patients with rheumatoid arthritis
IntroductionThe goal of this study was to investigate (1) the associations of rheumatoid arthritis (RA)-related inflammation or rheumatoid factor/anti-cyclic citrullinated peptide (anti-CCP)Expand
Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells
BackgroundSinularin isolated from the cultured soft coral Sinularia flexibilis has been reported to exert potent cytotoxic effects against particular types of cancer. This study was carried out toExpand
The beneficial effects of Lactobacillus reuteri ADR-1 or ADR-3 consumption on type 2 diabetes mellitus: a randomized, double-blinded, placebo-controlled trial
Probiotics have been reported to ameliorate symptoms of type 2 diabetes mellitus (T2DM) in animal models and human studies. We previously demonstrated that oral administration of LactobacillusExpand
Detecting the financial statement fraud: The analysis of the differences between data mining techniques and experts' judgments
TLDR
The objective of this study is to examine all aspects of fraud triangle using the data mining techniques and employ the available and public information to proxy variables to evaluate such attributes as pressure/incentive, opportunity, and attitude/rationalization, based on the findings from prior studies in this subject field and also the Statement on Auditing Standards. Expand
Chlorella sorokiniana induces mitochondrial-mediated apoptosis in human non-small cell lung cancer cells and inhibits xenograft tumor growth in vivo
BackgroundLung cancer is one of the leading causes of cancer related deaths worldwide. Marine microalgae are a source of biologically active compounds and are widely consumed as a nutritionalExpand
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