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Sharing healthcare data has become a vital requirement in healthcare system management; however, inappropriate sharing and usage of healthcare data could threaten patients’ privacy. In this article, we study the privacy concerns of sharing patient information between the Hong Kong Red Cross Blood Transfusion Service (BTS) and the public hospitals. We(More)
Sharing healthcare data has become a vital requirement in healthcare system management; however, inappropriate sharing and usage of healthcare data could threaten patients' privacy. In this paper, we study the privacy concerns of the blood transfusion information-sharing system between the Hong Kong Red Cross Blood Transfusion Service (BTS) and public(More)
BACKGROUND AND AIMS The association between HLA-DP single nucleotide polymorphisms (SNPs) and chronic hepatitis B virus (HBV) infection varies between different populations. We aimed to study the association between HLA-DP SNPs and HBV infection and disease activity in the Chinese population of Hong Kong. METHODS We genotyped SNPs rs3077 (near HLA-DPA1)(More)
BACKGROUND Experience from influenza pandemics suggested that convalescent plasma treatment given within 4 to 5 days of symptom onset might be beneficial. However, robust treatment data are lacking. METHODS This is a multicenter, prospective, double-blind, randomized controlled trial. Convalescent plasma from patients who recovered from the 2009 pandemic(More)
BACKGROUND Experience from treating patients with Spanish influenza and influenza A(H5N1) suggested that convalescent plasma therapy might be beneficial. However, its efficacy in patients with severe pandemic influenza A(H1N1) 2009 virus (H1N1 2009) infection remained unknown. METHODS During the period from 1 September 2009 through 30 June 2010, we(More)
BACKGROUND Little is known about the antibody response in natural infection by the novel 2009 influenza A (H1N1) virus and its relationship with clinical and virological parameters. The relative lack of background neutralizing antibody against this novel virus provides a unique opportunity for understanding this issue. METHODS Case patients presenting(More)
BACKGROUND The prevalence of human immunodeficiency virus (HIV) in men having sex with men (MSM) is generally higher than that in the average adult male population. In Hong Kong a permanent deferral mechanism is in place to minimise viral transmission during the window period. As regards donor deferral, the attitudes and behaviours of MSM in the community(More)
BACKGROUND Self-deferral of men having sex with men (MSM) from blood donation is a means of protecting blood safety. There has recently been a strategy change from permanent to time-limited deferral in some countries. Awareness and attitudes of donors is crucial for effective implementation of MSM deferral or any change of the strategy. STUDY DESIGN AND(More)
BACKGROUND AND AIMS The aim of the present study was to determine the population prevalence of occult hepatitis B (OHB) infection and its clinical profile in a highly endemic area of chronic hepatitis B virus disease. METHODS OHB was first identified by individual sample testing for hepatitis B surface antigen (HBsAg) followed by nucleic acid testing(More)
BACKGROUND Studies of the transmissibility of hepatitis B virus (HBV) in occult hepatitis B (OHB) through blood transfusion are scarce. We aimed to determine the transmissibility of HBV in blood donors with OHB through transfusion in animal and human studies. METHODS Among 217,595 blood donors, 67 donors with OHB were identified. Four chimeric mice(More)