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The cardiotonic activity of a new, noncatechol, nonglycoside agent, amrinone, was investigated in vitro and in anesthestized and unanesthetized dogs. Amrinone (3-100 microgram/ml) caused a… Continue Reading
1-R-3-Q-5-PY-6-R-2 (1H) -pyridinone of the formula: (CF DRAWING IN BOPI) wherein Q is a hydrogen atom, HYDROGEN OR A RADICAL amino, cYANO, carbamyl, HALO, lower alkylamino, DI (ALKYL lOWER) amino,… Continue Reading
RESPECT THE INVENTION OF COMPOUNDS OF FORMULA: (CF DRAWING IN BOPI) OR Q, R and R ARE EACH ATOM HYDROGEN GROUP OR LOWER ALKYL, PY IS A GROUP 4 - OR 3-optionally substituted pyridinyl, R AND R ARE… Continue Reading