Cheryl Booth

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Amyloid beta (Abeta) peptides derived from proteolytic cleavage of amyloid precursor protein (APP) are thought to be a pivotal toxic species in the pathogenesis of Alzheimer's disease (AD). Furthermore, evidence has been accumulating that components of APP processing pathway are involved in non-pathological normal function of the CNS. In this review we aim(More)
The endoplasmic reticulum (ER) contains a family of luminal proteins (reticuloplasmins) that are normally excluded from the secretory pathway. However, reticuloplasmins are efficiently secreted when murine fibroblasts are treated with calcium ionophores. The secreted and cellular forms of endoplasmin are clearly distinguishable on the basis of gel mobility(More)
Cardiac troponin (cTn) is a key biomarker for the assessment of myocardial injury, but overutilization of this test has increased workload and costs. We developed and implemented an algorithm to eliminate excessive utilization. Significant reduction was observed after the implementation of the algorithm in total cTnI requests (29.9%; P = .007), requests(More)
Language as a symbolic medium plays an important role in virtual communications. Words communicated online as action cues can provide indications of an actor's behavioral intent. This paper describes an ongoing investigation into the impact of a deceptive insider on group dynamics in virtual team collaboration. An experiment using an online game environment(More)
With an increasing number of online users, the potential danger of online deception grows accordingly - as does the importance of better understanding human behavior online to mitigate these risks. One critical element to address such online threat is to identify intentional deception in spontaneous online communication. For this study, we designed an(More)
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