Cheryl Augustine

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Following their generation in the germinal zones, young neurons of the neocortex, hippocampus and cerebellum undergo long-distance migration to reach their final destinations. This locomotive activity depends on active deployment of cytoskeletal elements including the microtubule apparatus. In this study, we report the identification and expression of(More)
Wnts are a family of secreted proteins involved in multiple developmental mechanisms during nervous system development, including cell proliferation, cell migration, axon guidance and specification of cell positional information. We report here the expression of sFRP-1 mRNA, encoding a putative inhibitor of Wnt, in the developing mouse neocortex during the(More)
Molecular inventories of the developing mouse neocortex before and after birth were generated using the global gene expression profiling tool serial analysis of gene expression (SAGE). Libraries were generated from embryonic day 15 and postnatal day 1 mouse neocortex and more than 40,000 tags were collected (20,211 and 22,001 tags, representing 11,706 and(More)
Members of the basic helix-loop-helix (bHLH) transcription factor family are crucial regulators of neuronal cell generation and cell fate. A number of bHLH genes are expressed in the developing cerebral cortex, including MASH-1, neurogenin2 and NeuroD implying the existence of a regulatory and possibly redundant network of family members. BETA3 is a novel(More)
The following corrections were made to this report: Section 7 Validation of JEDI Results pages 24 and 25. Page 24-Table 3, Row 3, Column 4: The number " 12 " has been changed to " 10 ". Source reference has been changed to " U.S. DOE Loan Programs Office 2012 " and the footnote has been changed as well. Similar reference on page 25 has been changed also.(More)
In the past decade, Quality of Service (QoS) parameters have posed great challenges for Network Operators. This is partly because of the growth in network varied traffic demands. The Internet is a best-effort technology, and therefore, not optimized for the transport of delay sensitive services. Real time voice, video, and some applications, such as(More)
Brain injury causes dysfunction of the blood-brain barrier (BBB). The BBB is comprised of perivascular astrocytes whose end-feet ensheath brain microvascular endothelial cells. We investigated trauma-induced morphological changes of human astrocytes (HA) and human cerebral microvascular endothelial cells (hCMEC/D3) in vitro, including the potential role of(More)
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