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The rapid discovery and identification of physalins in the calyx of Physalis alkekengi L.var.franchetii (Mast.) Makino using ultra-high performance liquid chromatography-quadrupole time of flight
TLDR
The fragmentation pathways and correspondingly fragmentation rules of physalins in negative MS/MS mode were thoroughly investigated in this study using seven physalin standards and an integrated approach using UHPLC-QTOF-MS/MS together with a novel three-step data mining strategy was developed for the systematic analysis of physAlins in complex samples. Expand
Hypolipidemic effects of Alismatis rhizome on lipid profile in mice fed high-fat diet.
TLDR
Alismatis rhizome may act by decreasing the liver synthesis of cholesterol, rather than by increasing the cholesterol catabolism, in mice fed high-fat diet and confirmed the efficacy of AR in the treatment of hyperlipidemia. Expand
Antidiabetic Effect of an Active Components Group from Ilex kudingcha and Its Chemical Composition
TLDR
Investigation of the antidiabetic activities of an active components group (ACG) obtained from Ilex kudingcha in alloxan-induced type 2 diabetic mice significantly reduced the elevated levels of serum glycaemic and lipids in type 1 diabetic mice. Expand
Anti-hyperglycemic effect of Potentilla discolor decoction on obese-diabetic (Ob-db) mice and its chemical composition.
TLDR
The anti-hyperglycemic effects of a clinical active extract (decoction) from P. discolor significantly attenuated the increase of blood glucose and cholesterol levels in Ob-db mice, and this is the first evidence for the presences of sulfated flavonoid in P. Discolor decoction. Expand
Identification and characterization of curcuminoids in turmeric using ultra-high performance liquid chromatography-quadrupole time of flight tandem mass spectrometry.
TLDR
The fragmentation behaviors of the 15 types of curcuminoids were clearly illustrated in this work, which will be helpful for detection and identification of corresponding trace cur cuminoids in complex turmeric samples using UHPLC-QTOF-MS/MS methods. Expand
A two-step approach for systematic identification and quality evaluation of wild and introduced Anemone flaccida Fr. Schmidt (Di Wu) based on DNA barcode and UPLC-QTOF-MS/MS
TLDR
The two-step approach provides a suitable strategy to evaluate the genuine quality of wild and introduced Anemone flaccida Fr. Expand
The metabolic change of serum lysophosphatidylcholines involved in the lipid lowering effect of triterpenes from Alismatis rhizoma on high-fat diet induced hyperlipidemia mice.
TLDR
It is demonstrated for the first time that triterpenes from the AR extract can lower serum lipid level in HFD induced hyperlipidemia mice and this understanding of the potential mechanism of lipid lowering effect of AR is improved. Expand
An integrated strategy for establishment of metabolite profile of endogenous lysoglycerophospholipids by two LC-MS/MS platforms.
TLDR
The integrated strategy for establishment of metabolite profile can be applied to targeted qualitative analysis of other endogenous metabolites which occur in a high individual number but sharing either structural similarities or similar functional groups. Expand
Preventive effects of turmeric on the high-fat diet-induced hyperlipidaemia in mice associated with a targeted metabolomic approach for the analysis of serum lysophosphatidylcholine using LC-MS/MS
TLDR
This is the first report regarding a targeted metabolomic approach for analyses of serum Lyso PCs and its application to interpretation of preventive effects of turmeric on mice hyperlipidaemia. Expand
An integrated strategy for establishment of curcuminoid profile in turmeric using two LC–MS/MS platforms
TLDR
The structural identification procedures of curcuminoids and the integrated strategy provide a suitable method to analyze targeted plant metabolites which occur in a high number but sharing either structural similarities or similar functional groups. Expand
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