Chengqian Zhou

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Adult astrocytes and their processes, identified by glial fibrillary acidic protein immunohistochemistry and by electron microscopy, migrate into superior cervical ganglia auto-transplanted into the choroid fissure or septal nuclei of adult rats. Migration routes were along the blood vessels, and along the Schwann cell bundles of the transplant.(More)
Adult superior cervical sympathetic ganglia were auto-transplanted, and adult nodose ganglia were homografted into the septal nuclei or the choroid fissure of adult Wistar rats. At times from 4 h to 9 weeks after operation, the distribution of surviving transplanted neurons was compared with the development of the transplant vascularization, as visualized(More)
Foetal mouse hippocampal primordia from mice homozygous for the Thy-1.1 allele were transplanted into the hippocampal region of adult histocompatible mice, homozygous for the Thy-1.2 allele. After survival periods of two months to one year the transplants consisted of a discrete tissue mass, well fused with the host, and distinguished from it by an intense(More)
The mouse Thy-1.1/Thy-1.2 allelic marking system is used to show that transplanted embryonic entorhinal cortex can reinnervate adult host hippocampi. The projection is limited to the appropriate terminal zones--viz. the outer two-thirds of the stratum moleculare of the dentate gyrus, and the stratum lacunosum-moleculare of the hippocampus--and extends for(More)
Immature dendritic cells (iDCs) are for cell transplantation; however, no method has yet been developed for in vivo monitoring the transplanted iDCs. We have explored the feasibility of using superparamagnetic iron oxide (SPIO) labeling and magnetic resonance imaging for in vivo tracking of transplanted iDCs and determined the effects of SPIO labeling on(More)
The hippocampus receives a complex pattern of afferent nerve fibres, segregated in such a way that the different types of afferent axons terminate in strictly demarcated, contiguous, but non-overlapping territories at different proximo-distal levels on the dendrites. In this paper we have used a mouse allelic marking system to show that the dentate,(More)
After partial deafferentation postsynaptic sites are reinnervated by local sprouting of remaining axons. We have investigated whether this process is sufficient to prevent new synapses being formed by transplanted embryonic tissue. We find that after unilateral entorhinal ablation endogenous sprouting by local axons is unable to reinnervate all the(More)
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