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Recent studies from our laboratory have begun to elucidate the role of agrin in zebrafish development. One agrin morphant phenotype that results from agrin knockdown is microphthalmia (reduced eye size). To begin to understand the mechanisms underlying the role of agrin in eye development, we have analyzed retina development in agrin morphants. Retinal(More)
Notch signaling pathway defines an evolutionarily conserved mechanism in cell-fate determination in a broad spectrum of developmental processes through local cell interactions. mind bomb (mib) encodes an E3 ubiquitin ligase that is involved in Notch activation through Delta ubiquitylation and internalization. To further dissect the function of Mib, two(More)
In this paper, an adaptive backstepping control scheme is proposed for stabilizing and controlling a class of uncertain chaotic systems. We firstly show that many chaotic systems as paradigms in the research of chaos can be transformed into a class of nonlinear systems in the feedback form. Unlike some existing control schemes for chaotic systems, no priori(More)
The extracellular matrix (ECM) is a dynamic composite of secreted proteins that play important roles in numerous biological processes such as tissue morphogenesis, differentiation and homeostasis. Furthermore, various diseases are caused by the dysfunction of ECM proteins. Therefore, identifying these important ECM proteins may assist in understanding(More)
The adaptive inverse control technology is utilized for induction machine (IM) control. Adaptive inverse control is actually an open-loop control scheme and so in the adaptive inverse control the instability problem caused by feedback control is avoided and the better dynamic performances can also be achieved. Linear LMS technique of adaptive inverse(More)
BACKGROUND Developmental exposure to ethanol has long been known to cause persisting neurobehavioral impairment. However, the neural and behavioral mechanisms underlying these deficits and the importance of exposure timing are not well-characterized. Given the importance of timing and sequence in neurodevelopment it would be expected that alcohol(More)
Alcohol is a teratogen that has diverse effects on brain and craniofacial development, leading to a constellation of developmental disorders referred to as fetal alcohol spectrum disorder (FASD). The molecular basis of ethanol insult remains poorly understood, as does the relationship between molecular and behavioral changes as a consequence of prenatal(More)
State-space models are proposed to represent multiple-input multiple-output (MIMO) frequency-selective wireless channels with the motivation of better model approximation and more robust channel equalization performance when the order of the channel model is lower that of the true channel. We develop a simple framework under which the equalizers for(More)