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Cellular Chaperonin CCTγ Contributes to Rabies Virus Replication during Infection
ABSTRACT Rabies, as the oldest known infectious disease, remains a serious threat to public health worldwide. The eukaryotic cytosolic chaperonin TRiC/CCT complex facilitates the folding of proteinsExpand
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Inhibition of Antiviral Innate Immunity by Birnavirus VP3 Protein via Blockage of Viral Double-Stranded RNA Binding to the Host Cytoplasmic RNA Detector MDA5
ABSTRACT Chicken MDA5 (chMDA5), the sole known pattern recognition receptor for cytoplasmic viral RNA in chickens, initiates type I interferon (IFN) production. Infectious bursal disease virus (IBDV)Expand
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The chaperonin CCTα is required for efficient transcription and replication of rabies virus
Negri bodies (NBs) are formed in the cytoplasm of rabies virus (RABV)‐infected cells and are accompanied by a number of host factors to NBs, in which replication and transcription occur. Here, it wasExpand
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Infectious Bursal Disease Virus Activates c-Src To Promote α4β1 Integrin-Dependent Viral Entry by Modulating the Downstream Akt-RhoA GTPase-Actin Rearrangement Cascade
ABSTRACT While the entry of infectious bursal disease virus (IBDV) is initiated by the binding of the virus to the two major receptors integrin and HSP90, the signaling events after receptor bindingExpand
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A Data-Driven Bottom-Up Approach for Spatial and Temporal Electric Load Forecasting
With the rapid urbanization, electrical infrastructure spreads to raw areas without existing loads. How to achieve accurate long-term load forecasts based on land use plans is a realistic problem. OnExpand
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Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway
Autophagy is an essential component of host innate and adaptive immunity. Viruses have developed diverse strategies for evading or utilizing autophagy for survival. The response of the autophagyExpand
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VP1 and VP3 Are Required and Sufficient for Translation Initiation of Uncapped Infectious Bursal Disease Virus Genomic Double-Stranded RNA
ABSTRACT Infectious bursal disease virus (IBDV) is a bisegmented double-strand RNA (dsRNA) virus of the Birnaviridae family. While IBDV genomic dsRNA lacks a 5′ cap, the means by which the uncappedExpand
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Comparative proteomics analysis of host cells infected with Brucella abortus A19
We carried out a proteomic analysis of THP‐1‐derived macrophages with and without Brucella abortus A19 (B. abortus A19) infection in order to study the cellular responses to B. abortus A19. TheExpand
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STAU1 binds to IBDV genomic double‐stranded RNA and promotes viral replication via attenuation of MDA5‐dependent β interferon induction
Infectious bursal disease virus (IBDV) infection triggers the induction of type IIFN, which is mediated by melanoma differentiation‐associated protein 5 recognition of the viral genomicExpand
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Electric Load Data Compression and Classification Based on Deep Stacked Auto-Encoders
With the development of advanced metering infrastructure (AMI), electrical data are collected frequently by smart meters. Consequently, the load data volume and length increase dramatically, whichExpand
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