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Long non-coding RNA NEAT1 promotes non-small cell lung cancer progression through regulation of miR-377-3p-E2F3 pathway
Recently, the long non-coding RNA (lncRNA) NEAT1 has been identified as an oncogenic gene in multiple cancer types and elevated expression of NEAT1 was tightly linked to tumorigenesis and cancer… Expand
Down-regulation of c-Met and Bcl2 by microRNA-206, activates apoptosis, and inhibits tumor cell proliferation, migration and colony formation
Hsa-miRNA-206 (miR-206), highly expressed in skeletal muscle, has recently been discovered to have anticancer properties in different tissues. However, the role of miR-206 on lung cancer is still… Expand
MicroRNA-187-3p mitigates non-small cell lung cancer (NSCLC) development through down-regulation of BCL6.
- Chengcao Sun, S. Li, +4 authors De-jia Li
- Medicine, Biology
- Biochemical and biophysical research…
- 26 February 2016
Hsa-microRNA-187-3p (miR-187-3p) has recently been discovered having anticancer efficacy in different organs. However, the role of miR-187-3p on non-small cell lung cancer (NSCLC) is still ambiguous.… Expand
Hsa-miR-139-5p inhibits proliferation and causes apoptosis associated with down-regulation of c-Met
Hsa-miRNA-139-5p (miR-139-5p) has recently been discovered having anticancer efficacy in different organs. However, the role of miR-139-5p on lung cancer is still ambiguous. In this study, we… Expand
Sulforaphane mitigates muscle fibrosis in mdx mice via Nrf2-mediated inhibition of TGF-β/Smad signaling.
Sulforaphane (SFN), an activator of NF-E2-related factor 2 (Nrf2), has been found to have an antifibrotic effect on liver and lung. However, its effects on dystrophic muscle fibrosis remain unknown.… Expand
Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2.
- Chengcao Sun, Cuili Yang, +6 authors De-jia Li
- Medicine, Chemistry
- Journal of applied physiology
- 15 January 2015
Sulforaphane (SFN), one of the most important isothiocyanates in the human diet, is known to have chemo-preventive and antioxidant activities in different tissues via activation of nuclear factor… Expand
Hsa-miR-326 targets CCND1 and inhibits non-small cell lung cancer development
Hsa-miRNA-326 (miR-326) has recently been discovered having anticancer efficacy in different organs. However, the role of miR-326 on non-small cell lung cancer (NSCLC) is still ambiguous. In this… Expand
MicroRNAs: A novel potential biomarker for diagnosis and therapy in patients with non‐small cell lung cancer
Lung cancer is still one of the most serious causes of cancer‐related deaths all over the world. MicroRNAs (miRNAs) are defined as small non‐coding RNAs which could play a pivotal role in… Expand
Red Meat Consumption and the Risk of Stroke: A Dose-Response Meta-analysis of Prospective Cohort Studies.
- Cuili Yang, L. Pan, Chengcao Sun, Yongyong Xi, Liang Wang, De-jia Li
- Journal of stroke and cerebrovascular diseases…
- 1 May 2016
BACKGROUND Prospective studies of red meat consumption and risk of stroke have provided inconsistent results. We aimed to assess this association by conducting a meta-analysis of prospective cohort… Expand
CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect.
- Liang Wang, Yongyong Xi, +4 authors De-jia Li
- Medicine, Biology
- Experimental and molecular pathology
- 1 April 2017
MiR-150, a member of small non-coding RNAs, has been proven to dysregulate in different types of tumor and bear on carcinogenesis and cancer prognosis by regulating the expression of a series of gene… Expand