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Long-term effect of stent placement in 115 patients with Budd-Chiari syndrome.
AIM To report the long-term effect of stent placement in 115 patients with Budd-Chiari syndrome (BCS). METHODS One hundred and fifteen patients with BCS were treated by percutaneous stent… Expand
Sirt6 suppresses hepatocellular carcinoma cell growth via inhibiting the extracellular signal‑regulated kinase signaling pathway.
Sirt6, a member of the mammalian sirtuin family, is a protein that is located in the nucleus and is an NAD+‑dependent deacetylase important in the control of metabolic activity and genome stability.… Expand
Mechanism of apoptotic effects induced selectively by ursodeoxycholic acid on human hepatoma cell lines.
- H. Liu, C. Qin, G. Han, H. Xu, M. Meng, Z. Yang
- Biology, Medicine
- World journal of gastroenterology
- 21 March 2007
AIM To investigate the effects of ursodeoxycholic acid (UDCA) on apoptosis and proliferation of hepatoma cell lines. METHODS Human hepatoma cell lines HepG2 and BEL 7402 were cultured in medium… Expand
Submucosal tunnelling endoscopic resection (STER) for the treatment of a case of huge esophageal tumor arising in the muscularis propria: a case report and review of literature.
BACKGROUND AND AIMS Endoscopic Interventional Treatment is of little trauma and less complications in the treatment of esophageal tumor and leads to faster recovery and fewer days of hospitalization.… Expand
The effect of ulinastatin on the small intestine injury and mast cell degranulation in a rat model of sepsis induced by CLP.
- Yi-jing Zhang, M. Li, M. Meng, M. Feng, C. Qin
- Biology, Medicine
- Experimental and toxicologic pathology : official…
- 1 September 2009
INTRODUCTION Sepsis could be initiated by the gastrointestinal tract injury and subsequent bacterial translocation. In the present experiment, we aimed to investigate effect of ulinastatin (UTI) on… Expand
OSU-03012, a non-cox inhibiting celecoxib derivative, induces apoptosis of human esophageal carcinoma cells through a p53/Bax/cytochrome c/caspase-9-dependent pathway
OSU-03012 is a celecoxib derivative devoid of cyclooxygenase-2 inhibitory activity. It was previously reported to inhibit the growth of some tumor cells through the AKT-signaling pathway. In the… Expand
Effect of ursodeoxycholic acid on TGF beta1/Smad signaling pathway in rat hepatic stellate cells.
BACKGROUND Hepatic fibrosis is the key stage of the pathological progress from hepatic injury to cirrhosis. Ursodeoxycholic acid (UDCA) has been known as having significant clinical therapeutic… Expand
Protective effects of ursodeoxycholic acid against immune-mediated liver fibrosis in rats.
BACKGROUND/AIMS Ursodeoxycholic acid (UDCA), a natural component of bile, has been synthesized to treat cholestatic liver diseases such as primary biliary cirrhosis. Broad biochemical changes in… Expand
Growth inhibition and gene induction in human hepatocellular carcinoma cell exposed to sodium 4-phenylbutanoate.
BACKGROUND Sodium 4-phenylbutanoate (NaPB) can induce cellular differentiation and cell cycle arrest. However, its potential anticancer properties in hepatocellular carcinoma and influence on normal… Expand
Expression and prognostic significance of vascular endothelial growth factor receptor 1 in hepatocellular carcinoma
Aims Activation of vascular endothelial growth factor receptor 1 (VEGFR-1) promotes invasiveness in some cancer cells. However, VEGFR-1 expression and its relationship with clinical features and… Expand