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Development and characterization of an orodispersible film containing drug nanoparticles.
In this study, a novel orodispersible film (ODF) containing drug nanoparticles was developed with the goal of transforming drug nanosuspensions into a solid dosage form and enhancing oralExpand
Self-discriminating fluorescent hybrid nanocrystals: efficient and accurate tracking of translocation via oral delivery.
The in vivo fate of nanocrystals is a controversial topic, i.e. dissolving versus integral absorption through the intestinal membrane. This is due to the lack of functional strategies to identifyExpand
Nanogel for dermal application of the triterpenoids isolated from Ganoderma lucidum (GLT) for frostbite treatment
Abstract Objective: The purpose of this study was to formulate stable Ganoderma lucidum (GLT) nanogels suitable for topical delivery with a view to improve the therapeutic effect for frostbite.Expand
A solid phospholipid-bile salts-mixed micelles based on the fast dissolving oral films to improve the oral bioavailability of poorly water-soluble drugs
The phospholipid-bile salts-mixed micelles (PL-BS-MMs) are potent carriers used for oral absorption of drugs that are poorly soluble in water; however, there are many limitations associated withExpand
Influence of drug physicochemical characteristics on in vitro transdermal absorption of hydrophobic drug nanosuspensions
Abstract The purpose of this paper was to study the influence of drug physicochemical characteristics on in vitro transdermal absorption of hydrophobic drug nanosuspensions. Four drug nanosuspensionsExpand
Nanostructured lipid carrier based topical gel of Ganoderma Triterpenoids for frostbite treatment.
The objective of this study was to prepare nanostructured lipid carrier (NLC)-based topical gel of Ganoderma Triterpenoids (GTs) and evaluate their effects on frostbite treatment. GT-NLCs wasExpand
[Preparation and in vitro anti-hepatic fibrosis evaluation of herpetone nanosuspensions].
Herpetone( HPT) is a bioactive lignan extracted from Herpetospermum pedunculosum,which can protect liver,lower aminotransferase and inhibit hepatitis B virus. However,HPT has a poor oralExpand
[Analysis on intestinal absorption of paeoniflorin lipid liquid crystalline nanoparticles via everted intestinal sacs].
To study the absorption kinetics of paeoniflorin lipid liquid crystalline nanoparticles (Pae-LLCN) in different intestinal segments of rats and compare them with paeoniflorin(Pae) solution. RatExpand
Formulation of pluronic F127/TPGS mixed micelles to improve the oral absorption of glycyrrhizic acid
Abstract Background: Glycyrrhizic acid (GL), a pentacyclic triterpenoid glycoside, has been used as a hepatoprotective agent for the treatment of acute and chronic hepatitis. However, its poorExpand
Improved stability and oral bioavailability of Ganneng dropping pills following transforming lignans of herpetospermum caudigerum into nanosuspensions.
The present study was designed to improve storage stability and oral bioavailability of Ganneng dropping pills (GNDP) by transforming lignans of Herpetospermum caudigerum (HL) composed of herpetrioneExpand
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