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Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges.
Surface-enhanced Raman spectroscopy (SERS) inherits the rich chemical fingerprint information on Raman spectroscopy and gains sensitivity by plasmon-enhanced excitation and scattering. In particular,Expand
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Label-free detection of native proteins by surface-enhanced Raman spectroscopy using iodide-modified nanoparticles.
Proteins perform vital functional and structural duties in living systems, and the in-depth investigation of protein in its native state is one of the most important challenges in the postgenomicExpand
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Label-free surface-enhanced Raman spectroscopy detection of DNA with single-base sensitivity.
Direct, label-free detection of unmodified DNA is a great challenge for DNA analyses. Surface-enhanced Raman spectroscopy (SERS) is a promising tool for DNA analyses by providing intrinsic chemicalExpand
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Rational Design and Synthesis of γFe2 O3 @Au Magnetic Gold Nanoflowers for Efficient Cancer Theranostics.
An γFe2 O3 @Au core/shell-type magnetic gold nanoflower-based theranostic nano-platform is developed. It is integrated with ultrasensitive surface-enhanced Raman scattering imaging, high-resolutionExpand
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BSA-coated nanoparticles for improved SERS-based intracellular pH sensing.
Local microenvironment pH sensing is one of the key parameters for the understanding of many biological processes. As a noninvasive and high sensitive technique, surface-enhanced Raman spectroscopyExpand
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Laser Power Dependent Surface-Enhanced Raman Spectroscopic Study of 4-Mercaptopyridine on Uniform Gold Nanoparticle-Assembled Substrates
MOST (973 Program) [2013 CB933703, 2011YQ03012406]; NSFC [21021120456, 21227004, 21321062]; Fundamental Research Funds for the Central Universities [2010121019]
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Drop-coating deposition and surface-enhanced Raman spectroscopies (DCDRS and SERS) provide complementary information of whole human tears
Raman spectroscopy has received increasing interest in biomedical applications because of its label-free and in vivo detection capabilities. The main challenge for a wider application lies in its lowExpand
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Rapid Determination of Antimicrobial Susceptibility by Stimulated Raman Scattering Imaging of D2O Metabolic Incorporation in a Single Bacterium
Abstract Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with appropriate antibiotics and slowing down the emergence of antibiotic‐resistant bacteria.Expand
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Mechanism of cellular uptake of graphene oxide studied by surface-enhanced Raman spectroscopy.
The last few years have witnessed rapid development of biological and medical applications of graphene oxide (GO), such as drug/gene delivery, biosensing, and bioimaging. However, little is knownExpand
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Tracking the intracellular drug release from graphene oxide using surface-enhanced Raman spectroscopy.
We have developed a graphene oxide (GO)-based nanoplatform simultaneously loaded with a chemical drug and Ag nanoparticles (NPs), and employed it to study the drug release from GO in living cells byExpand
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