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Insertion/deletion (indel) is one of the most common methods of protein sequence variation. Recent studies showed that indels could affect their flanking regions and they are important for protein function and evolution. Here, we describe the Indel Flanking Region Database (IndelFR, http://indel.bioinfo.sdu.edu.cn), which provides sequence and structure(More)
The amount of UF resin penetration into fibers, used for the production of medium density fiberboard (MDF), is unknown. To evaluate the relationship between resin viscosity and resin penetration depth, an experimental procedure involving confocal laser scanning microscopy (CLSM) and a Toluidine Blue O staining system was performed. The results indicate that(More)
An experiment was conducted to investigate the effects of drying methods, namely rotary drum, lab oven, microwave and air-drying, on the surface wettability of wood strands by the Wilhelmy plate method. The measurements included the surface contact angle, free energy, and liquid sorption capacity. Thirty industrial strands including southern yellow pine(More)
Genes associated with induced pluripotent stem cells (iPS genes) are several pivotal transcriptional factors, which are used to induce pluripotent stem cells from some adult somatic cells. The roles of these iPS genes and especially the signature for these iPS genes in colorectal cancer (CRC) are still unclear. Overexpressed Oct4 and Lin28 but(More)
In this study, we examined the protective effects of Danshen both on endothelial progenitor cells (EPCs) in patients with hypercholesterolemia and on in-vitro EPCs of healthy volunteers. In the clinical study, we randomly divided 24 subjects with hypercholesterolemia into two groups (the control group and the Danshen-treated group). At the end of two weeks(More)
An ideal vascular graft should have the ability to guide the regeneration of neovessels with structure and function similar to those of the native blood vessels. Regeneration of vascular smooth muscle cells (VSMCs) with circumferential orientation within the grafts is crucial for functional vascular reconstruction in vivo. To date, designing and fabricating(More)
Wood composite industry has focused on traditional wood fibre resources such as logs, wood chips and sawmill-residues for panel manufacturing. It is becoming necessary now for the wood composite panel industry to look for ways to utilize non-traditional forest resources such as forest residuals for panel manufacturing. A full factorial experimental design(More)
Ubiquitin specific protease 4 (USP4) is a deubiquitinating enzyme with key roles in the regulation of p53 and TGFβ signaling, suggesting its importance in tumorigenesis. However, the mechanisms and regulatory roles of USP4 in cancer, including colorectal cancer, remain largely elusive. Here, we present the first evidence that USP4 regulates the growth,(More)
Smoking is a major risk factor for atherosclerosis. In this study, we evaluated the effects of benzo[a]pyrene (BaP, a prominent component of tobacco smoke) on the function and pro-inflammatory response of human endothelial progenitor cells (EPCs). EPCs were isolated from umbilical cord blood and treated with different concentrations (10, 20 and 50 µmol/l)(More)
The conformational dynamics of the 10th type-III module of fibronectin (FN-III(10)) adsorbed on the perfect and three reduced rutile TiO(2)(110) surfaces with different types of defects was investigated by molecular dynamics (MD) simulations. Stable protein-surface complexes were presented in the four simulated models and were derived from the contributions(More)