Cheng-Dien Hsu

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Nutritional factors may be relative to attention-deficit hyperactive disorder (ADHD), although the pathogenic mechanism is still unknown. Based on the work of others, we hypothesized that children with ADHD have altered dietary patterns and fatty acid metabolism. Therefore, the aim of this study was to evaluate dietary patterns and the blood fatty acid(More)
Attention-deficit hyperactivity disorder (ADHD), a highly heritable neurodevelopmental disorder, is characterized by inattention and hyperactivity. The brain-derived neurotrophic factor (BDNF), a member of the neurotrophic factor family, is important for normal neuronal development. It has been proposed that BDNF may play a role in the therapeutic action(More)
The pro-inflammatory cytokine interleukin-1 beta has been implicated in the pathogenesis of major depressive disorder and in cognitive function decline in the elderly. This study tests the hypothesis that a biallelic functional polymorphism in the promoter region of the interleukin-1 beta gene (IL1B −511C/T) affects vulnerability to geriatric depression and(More)
AIM To determine the differences in the remission rate, recovery rate, functional improvement, and treatment adherence related to treatment with short-acting immediate-release methylphenidate (IR-MPH) and long-acting osmotic-release oral system-methylphenidate (OROS-MPH) in a naturalistic setting among Taiwanese children with attention-deficit-hyperactivity(More)
Attention deficit hyperactivity disorder (ADHD) is a complex genetic disorder that is caused by multiple heritable and environmental factors. Serotonergic system-related genes are likely to be involved in the mechanisms underlying ADHD, because serotonin dysregulation has been related to impulsive and aggressive behavior in children, and has thus been(More)
To the Editor: Substance abuse is a complex trait that is influenced by neurobiological, psychosocial, and environmental factors. While the ventral tegmental area/nucleus accumbens dopamine system is crucial to acute reward and the initiation of addiction, evidence suggests that permanent neuroplastic changes occur at the cellular and molecular levels that(More)
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