Cheng-Chi Wu

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BACKGROUND Animal behavior is governed by the activity of interconnected brain circuits. Comprehensive brain wiring maps are thus needed in order to formulate hypotheses about information flow and also to guide genetic manipulations aimed at understanding how genes and circuits orchestrate complex behaviors. RESULTS To assemble this map, we deconstructed(More)
This paper presents an evolution-based hierarchical feature fusion system that selects the dominant features among multiple feature vectors for ultrasonic liver tissue characterization. After extracting the spatial gray-level dependence matrices, multiresolution fractal feature vectors and multiresolution energy feature vectors, the system utilizes(More)
The characteristics and therapeutic potential of subtypes of mesenchymal stem cells (MSCs) are largely unknown. In this study, CD146+ and CD146– MSCs were separated from human umbilical cords, and their effects on regulatory T cells (Tregs), Th17 cells, chondrogenesis, and osteogenesis were investigated. Flow cytometry was used to quantify IL-6 and TGF-β1(More)
Brain research requires a standardized brain atlas to describe both the variance and invariance in brain anatomy and neuron connectivity. In this study, we propose a system to construct a standardized 3D Drosophila brain atlas by integrating labeled images from different preparations. The 3D fly brain atlas consists of standardized anatomical global and(More)
Model averaging is a widely used technique in biomedical applications. Two established model averaging methods, iterative shape averaging (ISA) method and virtual insect brain (VIB) method, have been applied to several organisms to generate average representations of their brain surfaces. However, without sufficient samples, some features of the average(More)
The segmentation of Drosophila mushroom bodies is highly demanded in the Dro-sophila brain research. In this work, we developed a template-based segmentation system with integration of the 3D average brain model. 3D registration and warping are performed to obtain the initial contours of the snake algorithm for the segmentation procedure. 3D models can be(More)
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