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Paper based point-of-care testing disc for multiplex whole cell bacteria analysis.
- Chen-Zhong Li, K. Vandenberg, +5 authors Eugenio Almeide
- Computer Science, Medicine
- Biosensors & bioelectronics
- 15 July 2011
In this paper, we describe the fabrication and testing of a multiplex immuno-disc sensor for the specific detection of Pseudomonas aeruginosa and Staphylococcus aureus. Expand
Co-culture Based Blood-brain Barrier In Vitro Model, a Tissue Engineering Approach using Immortalized Cell Lines for Drug Transport Study
- Z. Zhang, A. McGoron, E. Crumpler, Chen-Zhong Li
- Biology, Medicine
- Applied biochemistry and biotechnology
This study evaluated the feasibility of using commercially available immortalized cell lines in building an in vitro blood-brain barrier (BBB) co-culture model for preliminary drug development… Expand
Synthesis and Biological Evaluation of Novel Folic Acid Receptor-Targeted, β-Cyclodextrin-Based Drug Complexes for Cancer Treatment
Drug targeting is an active area of research and nano-scaled drug delivery systems hold tremendous potential for the treatment of neoplasms. In this study, a novel cyclodextrin (CD)-based… Expand
Amperometric micro-immunosensor for the detection of tumor biomarker.
- Shradha Prabhulkar, S. Alwarappan, G. Liu, Chen-Zhong Li
- Chemistry, Medicine
- Biosensors & bioelectronics
- 15 August 2009
In this paper, a highly sensitive, reagentless, electrochemical strategy is reported for the detection of a cancer biomarker-Vascular Endothelial Growth Factor (VEGF). Disc shaped carbon fiber… Expand
Biosensing approaches for rapid genotoxicity and cytotoxicity assays upon nanomaterial exposure.
The increased utilization of nanomaterials could affect human health and the environment due to increased exposure. Several mechanisms regarding the negative effects of nanomaterials have been… Expand
A paper electrode integrated lateral flow immunosensor for quantitative analysis of oxidative stress induced DNA damage.
A novel device combining electrochemical and colorimetric detection is developed for the rapid measurement of 8-hydroxy-2'-deoxyguanosine (8-OHdG), a DNA oxidative damage biomarker. The device takes… Expand
Whole cell based electrical impedance sensing approach for a rapid nanotoxicity assay.
A whole cell based biosensor for rapid real-time testing of human and environmental toxicity of nanoscale materials is reported. Recent studies measuring nanoparticle cytotoxicity in vitro provide a… Expand
Detection of antibodies directed at M. hyorhinis p37 in the serum of men with newly diagnosed prostate cancer
BackgroundRecent epidemiologic, genetic, and molecular studies suggest infection and inflammation initiate certain cancers, including cancers of the prostate. Over the past several years, our group… Expand
Bright Yellow Fluorescent Carbon Dots as a Multifunctional Sensing Platform for the Label-Free Detection of Fluoroquinolones and Histidine.
- W. Lu, Y. Jiao, +5 authors Chen-Zhong Li
- Materials Science, Medicine
- ACS applied materials & interfaces
- 9 November 2018
Owing to their diverse properties, fluorescent carbon dots (CDs) have attracted more attention and present enormous potential in development of sensors, bioimaging, drug delivery, microfluidics,… Expand
Sensitive detection of formamidopyrimidine-DNA glycosylase activity based on target-induced self-primed rolling circle amplification and magnetic nanoprobes.
We developed a novel approach to determine formamidopyrimidine DNA glycosylase (FPG) activity by taking advantage of target-induced self-primed rolling circle amplification (RCA) and magnetic… Expand