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Convolutional neural network (CNN) has been widely employed for image recognition because it can achieve high accuracy by emulating behavior of optic nerves in living creatures. Recently, rapid growth of modern applications based on deep learning algorithms has further improved research and implementations. Especially, various accelerators for deep CNN have(More)
Plant responses to ethylene are mediated by regulation of EBF1/2-dependent degradation of the ETHYLENE INSENSITIVE3 (EIN3) transcription factor. Here, we report that the level of EIL1 protein is upregulated by ethylene through an EBF1/2-dependent pathway. Genetic analysis revealed that EIL1 and EIN3 cooperatively but differentially regulate a wide array of(More)
Parkinson's disease (PD) is characterized by the selective vulnerability of the nigrostriatal dopaminergic circuit. Recently, loss-of-function mutations in the PTEN-induced kinase 1 (PINK1) gene have been linked to early-onset PD. How PINK1 deficiency causes dopaminergic dysfunction and degeneration in PD patients is unknown. Here, we investigate the(More)
Here we describe a novel mechanism for plasma membrane insertion of the delta opioid receptor (DOR). In small dorsal root ganglion neurons, only low levels of DORs are present on the cell surface, in contrast to high levels of intracellular DORs mainly associated with vesicles containing calcitonin gene-related peptide (CGRP). Activation of surface DORs(More)
Project ExScal (for extreme scale) fielded a 1000+ node wireless sensor network and a 200+ node peer-to-peer ad hoc network of 802.11 devices in a 13km by 300m remote area in Florida, USA during December 2004. In comparison with previous deployments, the ExScal application is relatively complex and its networks are the largest ones of either type fielded to(More)
Software development has traditionally been regarded as an activity that can only be effectively conducted and managed within a firm setting. However, contrary to such assertions, the open source software development (OSSD) approach, in which software developers in Internet-based communities coordinate to voluntarily contribute programming code, has(More)
Memory partitioning is widely adopted to efficiently increase the memory bandwidth by using multiple memory banks and reducing data access conflict. Previous methods for memory partitioning mainly focused on one-dimensional arrays. As a consequence, designers must flatten a multidimensional array to fit those methodologies. In this work we propose an(More)
Neuroligins (NLs) are postsynaptic cell-adhesion molecules essential for normal synapse function. Mutations in neuroligin-4 (NL4) (gene symbol: NLGN4) have been reported in some patients with autism spectrum disorder (ASD) and other neurodevelopmental impairments. However, the low frequency of NL4 mutations and the limited information about the affected(More)
Postsynaptic neuroligins are thought to perform essential functions in synapse validation and synaptic transmission by binding to, and dimerizing, presynaptic alpha- and beta-neurexins. To test this hypothesis, we examined the functional effects of neuroligin-1 mutations that impair only alpha-neurexin binding, block both alpha- and beta-neurexin binding,(More)
Pseudomonas aeruginosa CH7, isolated from activated sludge, was able not only to isomerize and degrade beta-cypermethrin but also to utilize it as the sole source of carbon and energy for growth and produce biosurfactant. The strain effectively degraded beta-cypermethrin with inocula biomass of 0.1-0.2 g L(-1) at 25-35°C, pH 6-9, and a final concentration(More)