• Publications
  • Influence
Mechanism and selectivity of bioinspired cinchona alkaloid derivatives catalyzed asymmetric olefin isomerization: a computational study.
TLDR
The computational results provided further theoretical evidence that the rate-limiting step of this bioinspired organocatalytic olefin isomerization is inconsistent with that of the enzyme catalyzed olefins catalyzed by novel cinchona alkaloid derivatives.
Enantioselective Allylation of Oxocarbenium Ions Catalyzed by Bi(OAc)3/Chiral Phosphoric Acid
TLDR
An asymmetric allylation of 3-hydroxyisobenzofuran-1(3H)-ones is disclosed, paving the way for the development of newPhthalides as the crucial core skeletons of biological active molecules.
Direct C–H difluoromethylation of heterocycles via organic photoredox catalysis
TLDR
An organophotocatalytic direct difluoromethylation of heterocycles using O 2 as green oxidant and preliminarily study the products’ bioactivity is shown.
Metal-Free Direct C-H Cyanoalkylation of Quinoxalin-2(1 H)-Ones by Organic Photoredox Catalysis.
TLDR
Green and efficient C-C bond cleavage/cyanoalkylation of quinoxalin-2(1 H)-ones and other heteroarenes under visible light or sunlight irradiation is described, enabling facile transformations to various significant organic compounds.
Atroposelective Catalytic Asymmetric Allylic Alkylation Reaction for Axially Chiral Anilides with Achiral Morita-Baylis-Hillman Carbonates.
TLDR
A broad range of axially chiral anilide products with different acyl groups, such as substituted phenyl, naphthyl, alkyl, enyl, styryl, and benzyl, were generated with very good yields, moderate to excellent cis: trans ratios, and good to excellent enantioselectivities.
Asymmetric Synthesis of Dihydrocoumarins through Chiral Phosphoric Acid-Catalyzed Cycloannulation of para-Quinone Methides and Azlactones.
TLDR
A chiral phosphoric acid-catalyzed approach constructing dihydrocoumarin motifs by the addition of azlactones to para-quinone methides (p-QMs) was developed and two possible pathways were proposed to explain the stereoselectivity.
9,10-Dicyanoanthracene Catalyzed Decarboxylative Alkynylation of Carboxylic Acids under Visible-Light Irradiation.
TLDR
This work represents the first example of an organophotocatalytic method for decarboxylative alkynylation of carboxylic acids with blue LED irradiation at room temperature under an atmosphere of argon.
Asymmetric Conjugate Addition of Benzofuran-2-ones to Alkyl 2-Phthalimidoacrylates: Modeling Structure-Stereoselectivity Relationships with Steric and Electronic Parameters.
TLDR
New 3,5-bis(trifluoromethyl)benzyl- and methyl-substituted tertiary amine thioureas turned out to be highly suitable catalysts for this reaction and enabled the synthesis of enantioenriched α-amino acid derivatives with 1,3-nonadjacent stereogenic centers.
Theoretical study on the acidities of chiral phosphoric acids in dimethyl sulfoxide: hints for organocatalysis.
TLDR
The pKa values of 41 chiral phosphoric acid-family catalysts in DMSO were predicted using the SMD/M06-2x/ 6-311++G(2df,2p)//B3LYP/6-31+G(d) method for the first time, indicating that this strategy may be suitable for calculating highly accurate pKa's.
...
1
2
3
4
...