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The Chlamydomonas reinhardtii nuclear gene gsa, which encodes the early chlorophyll biosynthetic enzyme glutamate 1-semialdehyde aminotransferase (GSAT), is specifically induced by blue light in cells synchronized in a 12-hr-light and 12-hr-dark regime. Light induction required the presence of a nitrogen source in the incubation medium. Maximal induction(More)
studies in finding correlations between genetic lesions and prognostic biomark-ers and, more importantly, in finding functionally critical drivers of leukemogenesis. 5-7 In this issue of Blood, Harvey and co-workers now confirm that children with B-precursor ALL, who have been classified as high risk on the basis of the simple clinical National Cancer(More)
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