Chelsea M Lee

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We comprehensively reviewed the irritable bowel syndrome (IBS) in terms of pathogenesis, psychiatric implications, general management and appropriate role of antidepressants, in particular selective serotonin uptake inhibitors (SSRIs) in the treatment of IBS. English language papers cited in MEDLINE and PychInfo from January 2000 to July 2006 were searched(More)
In a cross-sectional study, 34 diabetic patients with clinically significant macular edema underwent visual acuity testing, stereo fundus photography (graded for retinal thickening and hard exudates), fluorescein angiography (evaluated for macular leakage and the outline of the foveal avascular zone [FAZ]), and vitreous fluorophotometry (whereby posterior(More)
Improving glycaemic control in patients with type 2 diabetes reduces microvascular complications. The national service framework for diabetes and the new general medical service contract have been aiming to direct more focus on improving HbA1c. These measures have resulted in increasing number of patients being initiated on insulin therapy, which increases(More)
We obtained electroretinograms (ERGs) from normal subjects and from patients with sickle cell disease. The ERG components (a-wave, b-wave, and oscillatory potentials) obtained from normal subjects and patients without peripheral retinal neovascularization did not differ in either amplitude or implicit time. However, ERG components obtained from patients(More)
Among many antioxidants that are used for the repairing of oxidative stress induced skin damages, we identified the enriched astaxanthin extract (EAE) from Haematococcus pluvialis as a viable ingredient. EAE was extracted from the red microalgae through supercritical fluid carbon dioxide extraction. To compare the effectiveness, EAE wastreated on human(More)
Chorioretinal lesions produced by dye laser photocoagulation were examined on normal monkey retinas, using angiographic and histopathologic techniques. Retinal burns produced by green (514 nm), yellow (577 nm), orange (600 nm), and red (630 nm) laser lights were placed in the posterior pole between the fovea and the major vascular arcades. When examined(More)
Thumb twitch in response to "train-of-4" nerve stimulation was observed in 34 anesthetized patients receiving d-tubocurarine. Over the range of 75 to 100 percent block of the 1st twitch in the train, the 4th, 3rd, 2nd, and 1st twitch become undetectable, in that order. The reappearance of twitch by spontaneous recovery also occurs predictably, following the(More)