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Thiolated pyrrolidinyl peptide nucleic acids for the detection of DNA hybridization using surface plasmon resonance.
Thiolated pyrrolidinyl peptide nucleic acids (HS-PNAs) bearing d-prolyl-2-aminocyclopentanecarboxylic acid (ACPC) backbones with different lengths and types of thiol modifiers were synthesized andExpand
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Multilayer film assembled from charged derivatives of chitosan: physical characteristics and biological responses.
Polyelectrolyte multilayer films were successfully assembled from each of the three charged derivatives of chitosan; N-[(2-hydroxyl-3-trimethylammonium)propyl]chitosan chloride (HTACC), N-succinylExpand
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Comparison of DNA, aminoethylglycyl PNA and pyrrolidinyl PNA as probes for detection of DNA hybridization using surface plasmon resonance technique.
Pyrrolidinyl peptide nucleic acid bearing a D-prolyl-2-aminocyclopentanecarboxylic acid backbone (acpcPNA) has been evaluated as a new sensing probe for detection of DNA hybridization. In this study,Expand
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Pyrrolidinyl peptide nucleic acid with α/β-peptide backbone
We describe herein a new conformationally constrained analog of PNA carrying an alternating α/β amino acid backbone consisting of (2'R,4'R)-nucleobase-subtituted proline andExpand
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Detection of the shrimp pathogenic bacteria, Vibrio harveyi, by a quartz crystal microbalance-specific antibody based sensor
Abstract An immunosensor based on a quartz crystal microbalance (QCM) was developed for detection of Vibrio harveyi (V. harveyi), a pathogenic bacteria causing morbidity and even a high level ofExpand
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Surface plasmon resonance study of PNA interactions with double-stranded DNA.
Peptide nucleic acid (PNA) is a well known DNA analogue bearing a N-(2-aminoethyl)glycine backbone (aegPNA). This molecule is able to not only form a duplex with single stranded (ss) nucleic acidsExpand
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Synthesis and immobilization of thiolated pyrrolidinyl peptide nucleic acids on gold-coated piezoelectric quartz crystals for the detection of DNA hybridization
Abstract Two novel thiolated pyrrolidinyl peptide nucleic acids (HS-PNA) carrying d -prolyl-2-aminocyclopentane-carboxylic acid (ACPC) backbones were synthesized and directly immobilized onExpand
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Convenient Procedure for Synthesis of N‐Protected β‐Aminomalonates and β‐Amino Acids From α‐Amidosulfones
Abstract A synthesis of N‐protected β‐aminomalonates starting from α‐amidosulfones under very mild and simple reaction conditions is described. Treatment of the sulfones with malonate esters in theExpand
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