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Gene set enrichment testing can enhance the biological interpretation of ChIP-seq data. Here, we develop a method, ChIP-Enrich, for this analysis which empirically adjusts for gene locus length (the length of the gene body and its surrounding non-coding sequence). Adjustment for gene locus length is necessary because it is often positively associated with(More)
UNLABELLED Tests for differential gene expression with RNA-seq data have a tendency to identify certain types of transcripts as significant, e.g. longer and highly-expressed transcripts. This tendency has been shown to bias gene set enrichment (GSE) testing, which is used to find over- or under-represented biological functions in the data. Yet, there(More)
MOTIVATION Functional enrichment testing facilitates the interpretation of Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) data in terms of pathways and other biological contexts. Previous methods developed and used to test for key gene sets affected in ChIP-seq experiments treat peaks as points, and are based on the number(More)
This paper presents a human detection system using motion feature and adaptive boosting machine learning algorithm. The system will identify and detect human from the video captured in the outdoor environment. This research consists of three stages. The preliminary stage involves image preprocessing to segment out the motion region by reducing the noise.(More)
In this paper, we study the use of boosted weak classifiers selected with AdaBoost algorithm in object detection. Our work is motivated by the good performance of AdaBoost in selecting discriminative features and the effectiveness of Classification and Regression Tree (CART) compared with other classification methods. First, we study the cascaded structure(More)
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