Chay Leng Yeo

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The use of newer azoles as prophylaxis in hematological patients undergoing stem cell transplantation or immunosuppressive chemotherapy has been shown to decrease the risk of developing invasive fungal disease (IFD). However, the cost-effectiveness of such a strategy is dependent on the local epidemiology of IFD. We conducted an audit of hematological(More)
Antimicrobial stewardship is an emerging field currently defined by a series of strategies and interventions aimed toward improving appropriate prescription of antibiotics in humans in all healthcare settings. The ultimate goal is the preservation of current and future antibiotics against the threat of antimicrobial resistance, although improving patient(More)
Guidelines for Antimicrobial Stewardship Training and Practice Christine B Teng,1,5 MS(Clin Pharm), BCPS(AQ-ID), Winnie Lee,2 B.Pharm(Hon), BCPS(AQ-ID), Chay Leng Yeo,3 B.Pharm (Hon), BCPS, Siok Ying Lee,4 BSc(Pharmacy)(Hon), BCPS, Tat Ming Ng,5 BSc(Pharmacy)(Hon), Siang Fei Yeoh,3 MClinPharm, Wee Heng Lim,6 BSc(Pharmacy), Andrea L Kwa,2 PharmD,(More)
BACKGROUND Inappropriate prescription of antibiotics may contribute towards higher levels antimicrobial resistance. A key intervention for improving appropriate antibiotic prescription is surveillance of prescription. This paper presents the results of a longitudinal surveillance of broad-spectrum antibiotic prescription in 5 public-sector hospitals in(More)
The optimal way for antimicrobial stewardship programs (ASPs) to interact with existing infectious disease physician (IDP) services within the same institution is unknown. In our institution, IDPs and our prospective audit and feedback ASP operate independently, with occasionally differing recommendations offered for the same inpatient. We performed a(More)
Our prospective-audit-and-feedback antimicrobial stewardship (AS) program for hematology and oncology inpatients was switched from one led by dedicated clinicians to a rotating team of infectious diseases trainees in order to provide learning opportunities and attempt a “de-escalation” of specialist input towards a more protocol-driven implementation.(More)
The concept of antimicrobial resistance was already known even at the very nascence of modern antibiotics—it was famously sounded off by Alexander Fleming himself during his Nobel lecture in 1945. However, the subsequent decades from 1950s to 1970s saw the development and proliferation of multiple new classes of antibiotics, and this, coupled with the(More)
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