Charlotte S Mullan

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Running title: Tryptase regulates IL-8 expression. ABSTRACT Mast cells are central in the development of several allergic diseases and contain a number of pre-formed mediators.-tryptase, the most abundant mast cell product, is increasingly recognized as a key inflammatory mediator as it causes the release of cytokines, particularly the chemokine IL-8, from(More)
Mast cells are central in the development of several allergic diseases and contain a number of pre-formed mediators. beta-tryptase, the most abundant mast cell product, is increasingly recognized as a key inflammatory mediator, as it causes the release of cytokines, particularly the chemokine IL-8, from both inflammatory and structural cells. The molecular(More)
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