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Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP
Autism is a neurodevelopmental disorder characterized by abnormal reciprocal social interactions, communication deficits, and repetitive behaviors with restricted interests. BTBR T+tf/J (BTBR) is anExpand
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Sociability and motor functions in Shank1 mutant mice
Autism is a neurodevelopmental disorder characterized by aberrant reciprocal social interactions, impaired communication, and repetitive behaviors. While the etiology remains unclear, strong evidenceExpand
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Working memory deficits, increased anxiety-like traits, and seizure susceptibility in BDNF overexpressing mice.
BDNF regulates components of cognitive processes and has been implicated in psychiatric disorders. Here we report that genetic overexpression of the BDNF mature isoform (BDNF-tg) in female miceExpand
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Premotor Neuron Divergence Reflects Vocal Evolution
To identify mechanisms of behavioral evolution, we investigated the hindbrain circuit that generates distinct vocal patterns in two closely related frog species. Male Xenopus laevis and XenopusExpand
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Evolution of vocal patterns: tuning hindbrain circuits during species divergence
ABSTRACT The neural circuits underlying divergent courtship behaviors of closely related species provide a framework for insight into the evolution of motor patterns. In frogs, male advertisementExpand
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Feedback to the future: motor neuron contributions to central pattern generator function
ABSTRACT Motor behaviors depend on neural signals in the brain. Regardless of where in the brain behavior patterns arise, the central nervous system sends projections to motor neurons, which in turnExpand
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Inspiring song: The role of respiratory circuitry in the evolution of vertebrate vocal behavior
Vocalization is a common means of communication across vertebrates, but the evolutionary origins of the neural circuits controlling these behaviors are not clear. Peripheral mechanisms of soundExpand
Generation, Coordination, and Evolution of Neural Circuits for Vocal Communication
In many species, vocal communication is essential for coordinating social behaviors including courtship, mating, parenting, rivalry, and alarm signaling. Effective communication requires accurateExpand
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