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Prepulse inhibition (PPI) is the inhibition of an acoustic startle response (ASR) that is observed when a weak prepulse is presented shortly before a startling stimulus. Here we studied in Wistar rats the dependence of PPI on variations of the interstimulus interval (ISI; from 25-1020ms) after treatment with various drugs that are known to disrupt PPI. The(More)
RATIONALE The interactions between Δ(9)-tetrahydrocannabinol (THC) and cannabidiol (CBD) during chronic treatment, and at equivalent doses, are not well characterised in animal models. OBJECTIVES The aim of this study is to examine whether the behavioural effects of THC, and blood and brain THC levels are affected by pre-treatment with equivalent CBD(More)
Obesity is currently one of the most serious threats to human health in the western civilization. A growing body of evidence suggests that obesity is associated with cognitive dysfunction. Physical exercise not only improves fitness but it has also been shown in human and animal studies to increase hippocampus-dependent learning and memory. High-fat diet(More)
The mechanical network of the brain is a major contributor to neural health and has been recognized by in vivo magnetic resonance elastography (MRE) to be highly responsive to diseases. However, until now only brain softening was observed and no mechanism was known that reverses the common decrement of neural elasticity during aging or disease. We used MRE(More)
The biomechanical properties of brain tissue are altered by histopathological changes due to neurodegenerative diseases like Parkinson's disease (PD). Such alterations can be measured by magnetic resonance elastography (MRE) as a non-invasive technique to determine viscoelastic parameters of the brain. Until now, the correlation between histopathological(More)
In the context of television consumption and its opportunity costs the question arises how far experiencing mere representations of the outer world would have the same neural and cognitive consequences than actively interacting with that environment. Here we demonstrate that physical interaction and direct exposition are essential for the beneficial effects(More)
  • Marissa Karomfily, Emily Smedley, Julia Maltz, Copy Editor, Jennifer Ewald, Joanne Piombino +9 others
  • 2015
undergraduate student research in all areas of linguistics. The journal is directly overseen by an undergraduate student editor and reviewers with input from linguistics faculty. SUBMISSION INFORMATION Submissions are welcomed from undergraduate student authors currently specializing in any discipline (authors are not required to be linguistics majors or(More)
  • Abigail Gorman, Jimson Mathew, Emily Smedley, Copy Editor, Jennifer Ewald, Joanne Piombino +7 others
  • 2015
undergraduate student research in all areas of linguistics. The journal is directly overseen by an undergraduate student editor and reviewers with input from linguistics faculty. SUBMISSION INFORMATION Submissions are welcomed from undergraduate student authors currently specializing in any discipline (authors are not required to be linguistics majors or(More)
  • Julia Maltz, Emily Smedley, Copy Editor, Jennifer Ewald, Joanne Piombino, Carlo Cinaglia +7 others
  • 2014
undergraduate student research in all areas of linguistics. The journal is directly overseen by an undergraduate student editor and reviewers with input from linguistics faculty. SUBMISSION INFORMATION Submissions are welcomed from undergraduate student authors currently specializing in any discipline (authors are not required to be linguistics majors or(More)
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