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A mAb (1E5) that binds the COOH-terminal region of the beta subunit of chicken CapZ inhibits the ability of CapZ to bind the barbed ends of actin filaments and nucleate actin polymerization. CapZ prepared as fusion proteins in bacteria or nonfusion proteins by in vitro translation has activity similar to that of CapZ purified from muscle. Deletion of the(More)
Process mining aims to discover, enhance or check the conformance of activity-oriented process models from event logs. A new field of research, called intention mining, recently emerged. This field has the same objectives as process mining but specifically addresses intentional process models (processes focused on the reasoning behind the activities). This(More)
Research on guidance and method engineering has highlighted that many method engineering issues, such as lack of flexibility or adaptation, are solved more effectively when intentions are explicitly specified. However, software engineering process models are most often described in terms of sequences of activities. This paper presents a novel approach,(More)
So far, process mining techniques have suggested to model processes in terms of tasks that occur during the enactment of a process. However, research on method engineering and guidance has illustrated that many issues, such as lack of flexibility or adaptation, are solved more effectively when intentions are explicitly specified. This paper presents a novel(More)
Capping protein controls the addition of actin subunits to the barbed end of actin filaments and nucleates actin polymerization in vitro. Capping protein has been identified in all eukaryotic cells examined so far; it is a heterodimer with subunits of relative molecular masses 32,000-36,000 (alpha-subunit) and 28,000-32,000 (beta-subunit). In skeletal(More)
Since several decades, discovering process models is a subject of interest in the Information System (IS) community. Approaches have been proposed to recover process models, based on the recorded sequential tasks (traces) done by IS's actors. However, these approaches only focused on activities and the process models identified are, in consequence,(More)
Map formalism allows specifying processes with a high level of variability. However, this means many variation points, and therefore we need guidance to enact maps by customizing them. Traditional guidance consists in raising decision points to navigate in a map. The limit is that many decision points are raised at the same time, and the user (who enacts(More)
Several process metamodels exist. Each of them presents a different viewpoint of the same information systems engineering process. However, there are no existing correspondences between them. We propose a method to build unified, fitted and multi-viewpoint process metamodels for information systems engineering. Our method is based on a process domain(More)