Charles W. Duval

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The four cultures which form the basis of this communication were recovered from peculiar cases of primary cervical adenitis in man, three of which terminated fatally of disseminated acute miliary tuberculosis in four to six weeks. A careful comparative study shows that Culture II corresponds closely with the "human" and Culture IV with the "bovine" type of(More)
The bacillus of glanders may be so modified in virulence as to produce experimentally lesions differing widely in their histological features. The highly virulent culture causes primary necrosis and disintegration of the tissue followed by the invasion of the injured area by polymorphonuclear leucocytes. The bacilli of moderate virulence give rise to a(More)
According to our present conception of pigment-producing cells melanotic tumors do not occur outside the skin, eye and central nervous system, except as metastatic growths. Pigmented tumors that arise in the internal organs are traced in almost every case to a primary growth in a situation where pigment cells normally exist. Most commonly the black moles of(More)
1. Broth-grown cultures, cultures from blood agar slants and culture filtrates (Berkefeld N or V) of H. Streptococcus scarlatinae are without appreciable effect upon the rabbit, no matter how large the dose or by what route introduced. 2. The active toxic principle of H. Streptococcus scarlatinae for rabbits is intimately associated with the protein of the(More)
1. There is present as a causal agent in the nasopharyngeal secretions of measles cases a filter-passing virus. 2. The rabbit and the guinea pig react specifically to the intratracheal and intracirculatory injections of filtered nasopharyngeal secretions secured from cases of human measles. 3. Enanthem, exanthem, and pyrexial disturbances characterize this(More)
In general it may be said that three striking alterations occurred constantly in the animals reacting to intracardiac injections of blood from cases of measles; namely, pyrexia, leucopenia, and nephritis. The elevation in temperature usually began about the 9th day following inoculation, the rise being fairly abrupt from the normal to 104 degrees F. and(More)
The cutaneous reaction demonstrates that the culture lysate of Streptococcus scarlatinae is approximately ten time more potent in its toxic effect than is the culture filtrate since repeated and carefully controlled human skin tests show that 0.1 cc. of a 1:2000 dilution of lysate reacts equally as well as a similar dose of a 1:250 dilution of culture(More)