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BACKGROUND Blood pressure (BP) level is a major determinant of cardiovascular morbidity and mortality in individuals with diabetes mellitus. Several guidelines recommend lower BP goals and specific drug classes for these patients. The overviews reported herein were performed to formally compare the effects on cardiovascular events and death of different(More)
BACKGROUND As maternal deaths become rare in many countries, severe maternal morbidity has been suggested as a better indicator of quality of care. OBJECTIVE To develop and validate an indicator for measuring major maternal morbidity in routinely collected population health datasets (PHDS). METHODS First, diagnoses and procedures that might indicate(More)
BACKGROUND Administrative or population health datasets (PHDS) are increasingly being used for research related to maternal and infant health. However, the accuracy and completeness of the information in the PHDS is important to ensure validity of the results of this research. OBJECTIVE To compile and review studies that validate the reporting of(More)
OBJECTIVE To describe the investigation and management of patients admitted to hospitals in China with suspected acute coronary syndromes (ACS) and to identify potential areas for improvement in practice. DESIGN A multicentre prospective survey of sociodemographic characteristics, medical history, clinical features, in-hospital investigations, treatment(More)
BACKGROUND Low serum 25-hydroxyvitamin D [25(OH)D] concentrations during pregnancy have been associated with adverse pregnancy outcomes in a few studies but not in other studies. OBJECTIVES We assessed the serum 25(OH)D concentration at 10-14 wk of pregnancy and its association with adverse pregnancy outcomes and examined the predictive accuracy. DESIGN(More)
The aim was to develop a composite outcome indicator to identify infants with severe adverse outcomes in routinely collected population health datasets, and assess the indicator's association with readmission and infant mortality rates. A comprehensive list of diagnoses and procedures indicative of serious neonatal morbidity was compiled based on literature(More)
OBJECTIVE To examine seasonality of pregnancy hypertension rates, and whether they related to sunlight levels around conception. STUDY DESIGN Data were obtained for 424,732 singleton pregnancies conceived from 2001 through 2005 in Australia. We analyzed monthly rates of pregnancy hypertension and preeclampsia in relation to monthly solar radiation. (More)
OBJECTIVE To determine whether women delivering their first child at age 35 years or older are at increased risk of adverse (non-genetic) pregnancy outcomes. DESIGN AND SETTING A cross-sectional analytic study of singleton deliveries in Northern Sydney Area Health Service (NSAHS) hospitals. PARTICIPANTS All women aged > or = 20 years delivering their(More)
OBJECTIVE To quantify the relative risk reductions achieved with different regimens to lower blood pressure in younger and older adults. DESIGN Meta-analyses and meta-regression analyses used to compare the effects on the primary outcome between two age groups (<65 v > or =65 years). Evidence for an interaction between age and the effects of treatment(More)
OBJECTIVE The objective of this study was to compare international trends in pre-eclampsia rates and in overall pregnancy hypertension rates (including gestational hypertension, pre-eclampsia and eclampsia). DESIGN Population data (from birth and/or hospital records) on all women giving birth were available from Australia (two states), Canada (Alberta),(More)